Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/100789
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dc.contributor.authorMathieson, I.en
dc.contributor.authorLazaridis, I.en
dc.contributor.authorRohland, N.en
dc.contributor.authorMallick, S.en
dc.contributor.authorPatterson, N.en
dc.contributor.authorRoodenberg, S.en
dc.contributor.authorHarney, E.en
dc.contributor.authorStewardson, K.en
dc.contributor.authorFernandes, D.en
dc.contributor.authorNovak, M.en
dc.contributor.authorSirak, K.en
dc.contributor.authorGamba, C.en
dc.contributor.authorJones, E.en
dc.contributor.authorLlamas, B.en
dc.contributor.authorDryomov, S.en
dc.contributor.authorPickrell, J.en
dc.contributor.authorArsuaga, J.en
dc.contributor.authorDe Castro, J.en
dc.contributor.authorCarbonell, E.en
dc.contributor.authorGerritsen, F.en
dc.contributor.authoret al.en
dc.date.issued2015en
dc.identifier.citationNature, 2015; 528(7583):499-503en
dc.identifier.issn0028-0836en
dc.identifier.issn1476-4687en
dc.identifier.urihttp://hdl.handle.net/2440/100789-
dc.descriptionPublished online 23 November 2015en
dc.description.abstractAncient DNA makes it possible to observe natural selection directly by analysing samples from populations before, during and after adaptation events. Here we report a genome-wide scan for selection using ancient DNA, capitalizing on the largest ancient DNA data set yet assembled: 230 West Eurasians who lived between 6500 and 300 bc, including 163 with newly reported data. The new samples include, to our knowledge, the first genome-wide ancient DNA from Anatolian Neolithic farmers, whose genetic material we obtained by extracting from petrous bones, and who we show were members of the population that was the source of Europe's first farmers. We also report a transect of the steppe region in Samara between 5600 and 300 bc, which allows us to identify admixture into the steppe from at least two external sources. We detect selection at loci associated with diet, pigmentation and immunity, and two independent episodes of selection on height.en
dc.description.statementofresponsibilityIain Mathieson ... Bastien Llamas ... Alan Cooper ... Wolfgang Haak ... et al.en
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.rights© 2015 Macmillan Publishers Limited. All rights reserveden
dc.subjectBone and Bonesen
dc.titleGenome-wide patterns of selection in 230 ancient Eurasiansen
dc.typeJournal articleen
dc.identifier.rmid0030039700en
dc.identifier.doi10.1038/nature16152en
dc.relation.granthttp://purl.org/au-research/grants/arc/DP130102158en
dc.identifier.pubid222234-
pubs.library.collectionAustralian Centre for Ancient DNA publicationsen
pubs.library.teamDS03en
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidLlamas, B. [0000-0002-5550-9176]en
dc.identifier.orcidCooper, A. [0000-0002-7738-7851]en
dc.identifier.orcidHaak, W. [0000-0003-2475-2007]en
Appears in Collections:Australian Centre for Ancient DNA publications

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