Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/103863
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Type: Journal article
Title: Recording duration and short-term reproducibility of heart rate and QT interval variability in patients with myocardial infarction
Author: Yaghini Bonabi, S.
El-Hamad, F.
Müller, A.
Dommasch, M.
Steger, A.
Schmidt, G.
Baumert, M.
Citation: Physiological Measurement, 2016; 37(11):1925-1933
Publisher: IOP Publishing
Issue Date: 2016
ISSN: 0967-3334
1361-6579
Statement of
Responsibility: 
Safa Yaghini Bonabi, Fatima El-Hamad, Alexander Müller, Michael Dommasch, Alexander Steger, Georg Schmidt and Mathias Baumert
Abstract: Beat-to-beat variability of the QT interval (QTV) measured on surface ECG has emerged as a potential marker for ventricular repolarization instability and has been used along with heart rate variability (HRV) to predict arrhythmic risk. Since measurement modalities of QTV have not been standardized, the objective of this study was to investigate the effect of ECG recording duration on QTV as well as HRV. Using a database of 30 min ECG recorded from 500 patients with acute myocardial infraction during rest, we extracted RR and QT interval time series and estimated different HRV and QTV metrics over windows of varying length. Analysis of variance (ANOVA) and intra-class correlation analyses were computed to investigate the effect of recording length on consistency and short-term reproducibility of HRV and QTV variables. Good consistency (non-significant ANOVA results) and short-term reproducibility (intra-class correlation coefficients  >0.8) were demonstrated for all but standard deviation based metrics when at least 200 beats were included in the estimation. In conclusion, QTV can be quantified from resting ECG with good short-term consistency and reproducibility that is comparable to that of HRV.
Keywords: Heart rate variability; QT interval variability; myocardial infarction; recording length
Rights: © 2016 Institute of Physics and Engineering in Medicine
RMID: 0030055989
DOI: 10.1088/0967-3334/37/11/1925
Grant ID: http://purl.org/au-research/grants/arc/DP110102049
Appears in Collections:Electrical and Electronic Engineering publications

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