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https://hdl.handle.net/2440/109156
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dc.contributor.author | Bauer, M. | - |
dc.contributor.author | Glenn, T. | - |
dc.contributor.author | Alda, M. | - |
dc.contributor.author | Aleksandrovich, M. | - |
dc.contributor.author | Andreassen, O. | - |
dc.contributor.author | Angelopoulos, E. | - |
dc.contributor.author | Ardau, R. | - |
dc.contributor.author | Ayhan, Y. | - |
dc.contributor.author | Baethge, C. | - |
dc.contributor.author | Bharathram, S. | - |
dc.contributor.author | Bauer, R. | - |
dc.contributor.author | Baune, B. | - |
dc.contributor.author | Becerra-Palars, C. | - |
dc.contributor.author | Bellivier, F. | - |
dc.contributor.author | Belmaker, R. | - |
dc.contributor.author | Berk, M. | - |
dc.contributor.author | Bersudsky, Y. | - |
dc.contributor.author | Bicakci, S. | - |
dc.contributor.author | Birabwa-Oketcho, H. | - |
dc.contributor.author | Bjella, T. | - |
dc.contributor.author | et al. | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | Acta Psychiatrica Scandinavica, 2017; 136(6):571-582 | - |
dc.identifier.issn | 0001-690X | - |
dc.identifier.issn | 1600-0447 | - |
dc.identifier.uri | http://hdl.handle.net/2440/109156 | - |
dc.description | Accepted for publication June 16, 2017 | - |
dc.description.abstract | Objective: To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder. Method: Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth-cohort, family history, polarity of first episode and country physician density. Results: There was a significant, inverse association between the maximum monthly increase in solar insolation at the onset location, and the age of onset. This effect was reduced in those without a family history of mood disorders and with a first episode of mania rather than depression. The maximum monthly increase occurred in springtime. The youngest birth-cohort had the youngest age of onset. All prior relationships were confirmed using both the entire sample, and only the youngest birth-cohort (all estimated coefficients P < 0.001). Conclusion: A large increase in springtime solar insolation may impact the onset of bipolar disorder, especially with a family history of mood disorders. Recent societal changes that affect light exposure (LED lighting, mobile devices backlit with LEDs) may influence adaptability to a springtime circadian challenge. | - |
dc.description.statementofresponsibility | M. Bauer ... B. Baune ... et al. | - |
dc.language.iso | en | - |
dc.publisher | John Wiley & Sons | - |
dc.rights | © 2017 John Wiley & Sons A/S | - |
dc.source.uri | http://dx.doi.org/10.1111/acps.12772 | - |
dc.subject | bipolar disorder | - |
dc.subject | circadian rhythm | - |
dc.subject | epidemiology | - |
dc.subject | solar insolation | - |
dc.title | Solar insolation in springtime influences age of onset of bipolar I disorder | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/acps.12772 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/1059660 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Baune, B. [0000-0001-6548-426X] | - |
Appears in Collections: | Aurora harvest 3 Medical Sciences publications |
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