Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/112963
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Type: Journal article
Title: Latent profiles of early developmental vulnerabilities in a New South Wales child population at age 5 years
Author: Green, M.
Tzoumakis, S.
Laurens, K.
Dean, K.
Kariuki, M.
Harris, F.
O Reilly, N.
Chilvers, M.
Brinkman, S.
Carr, V.
Citation: Australian and New Zealand Journal of Psychiatry, 2018; 52(6):530-541
Publisher: SAGE Publications
Issue Date: 2018
ISSN: 0004-8674
1440-1614
Statement of
Responsibility: 
Melissa J Green, Stacy Tzoumakis, Kristin R Laurens, Kimberlie Dean, Maina Kariuki, Felicity Harris, Nicole O, Reilly, Marilyn Chilvers, Sally A Brinkman and Vaughan J Carr
Abstract: Objective: Detecting the early emergence of childhood risk for adult mental disorders may lead to interventions for reducing subsequent burden of these disorders. We set out to determine classes of children who may be at risk for later mental disorder on the basis of early patterns of development in a population cohort, and associated exposures gleaned from linked administrative records obtained within the New South Wales Child Development Study. Methods: Intergenerational records from government departments of health, education, justice and child protection were linked with the Australian Early Development Census for a state population cohort of 67,353 children approximately 5 years of age. We used binary data from 16 subdomains of the Australian Early Development Census to determine classes of children with shared patterns of Australian Early Development Census–defined vulnerability using latent class analysis. Covariates, which included demographic features (sex, socioeconomic status) and exposure to child maltreatment, parental mental illness, parental criminal offending and perinatal adversities (i.e. birth complications, smoking during pregnancy, low birth weight), were examined hierarchically within latent class analysis models. Results: Four classes were identified, reflecting putative risk states for mental disorders: (1) disrespectful and aggressive/ hyperactive behaviour, labelled ‘misconduct risk’ (N = 4368; 6.5%); (2) ‘pervasive risk’ (N = 2668; 4.0%); (3) ‘mild generalised risk’ (N = 7822; 11.6%); and (4) ‘no risk’ (N = 52,495; 77.9%). The odds of membership in putative risk groups (relative to the no risk group) were greater among children from backgrounds of child maltreatment, parental history of mental illness, parental history of criminal offending, socioeconomic disadvantage and perinatal adversities, with distinguishable patterns of association for some covariates. Conclusion: Patterns of early childhood developmental vulnerabilities may provide useful indicators for particular mental disorder outcomes in later life, although their predictive utility in this respect remains to be established in longitudinal follow-up of the cohort.
Keywords: Early childhood; record linkage; risk profiles; mental health; children
Rights: © The Royal Australian and New Zealand College of Psychiatrists 2017
RMID: 0030077370
DOI: 10.1177/0004867417740208
Grant ID: http://purl.org/au-research/grants/arc/LP110100150
http://purl.org/au-research/grants/nhmrc/1058652
http://purl.org/au-research/grants/nhmrc/1061875
Appears in Collections:Public Health publications

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