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Type: Journal article
Title: Cognitive dysfunction in major depressive disorder
Author: Knight, M.
Baune, B.
Citation: Current opinion in psychiatry, 2018; 31(1):26-31
Publisher: Wolters Kluwer Health
Issue Date: 2018
ISSN: 0951-7367
Statement of
Matthew J. Knight, Bernhard T. Baune
Abstract: Purpose of review: The principal aim of this review is to highlight recent advances in our understanding of cognitive dysfunction in major depressive disorder (MDD). We review new assessment and treatment approaches, in which cognition and associated psychosocial dysfunction are considered primary outcomes. Recent findings: Current work suggests that cognitive dysfunction reduces occupational productivity, and interferes broadly with domains of day-to-day and social functioning. These findings imply that cognitive dysfunction interacts with emotional and social factors relevant to MDD. Recent advances in screening instruments enable standardized detection of cognitive symptoms in MDD. Clinical trials suggest that cognitive symptoms are suitable targets and primary outcomes of psychological and pharmacological treatments. Summary: A growing interest in cognitive dysfunction in MDD has improved our ability to assess and treat MDD. Future research will be strengthened by the use of consistent terminology, standardized cognitive screening, and treatments that target cognitive dysfunction in MDD. Integration of emotional and social treatment strategies may further advance clinical efficacy.
Keywords: Cognition; cognitive remediation; cognitive training; executive functioning; major depressive disorder; screening, treatment
Rights: © 2017 Wolters Kluwer Health, Inc. All rights reserved.
RMID: 0030077018
DOI: 10.1097/yco.0000000000000378
Appears in Collections:Psychology publications

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