Please use this identifier to cite or link to this item:
Scopus Web of ScienceĀ® Altmetric
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPortelli, R.-
dc.contributor.authorDodd, I.-
dc.contributor.authorXue, Q.-
dc.contributor.authorEgan, J.-
dc.identifier.citationVirology, 1998; 248(1):117-130-
dc.descriptionCopyright 1998 Academic Press-
dc.description.abstractThe late-lytic region of the genome of bacteriophage 186 encodes the phage proteins that synthesize the complex viral particle and lyse the bacterial host. We report the completion of the DNA sequence of the late region and the assignment of 18 previously identified genes to open reading frames in the sequence. The 186 late region is similar to the late region of phage P2, sharing 26 genes of known function: the single gene for activation of late gene transcription, 6 genes for construction of DNA-containing heads, 16 for tail morphogenesis, and 3 for cell lysis. We identified two 186 late genes with unknown function; one is homologous to previously unrecognised genes in P2, HP1, and fCTX, and the other may modulate DNA packaging. The 186 late region, like the rest of the genome, lacks the lysogenic conversion genes that are carried by P2, allowing the 186 late region to be transcribed from only three late promoters rather than four. The relative absence of lysogenic conversion genes in 186 suggests that the two phages have evolved to use the lytic and lysogenic reproductive modes to different extents.-
dc.description.statementofresponsibilityRoberto Portelli, Ian B. Dodd, Qing Xue and J. Barry Egan-
dc.subjectEscherichia coli-
dc.subjectBacteriophage P2-
dc.subjectViral Proteins-
dc.subjectDNA, Viral-
dc.subjectSequence Alignment-
dc.subjectAmino Acid Sequence-
dc.subjectBase Sequence-
dc.subjectSequence Homology, Amino Acid-
dc.subjectSequence Homology, Nucleic Acid-
dc.subjectGenes, Viral-
dc.subjectGenome, Viral-
dc.subjectOpen Reading Frames-
dc.subjectMolecular Sequence Data-
dc.subjectPromoter Regions, Genetic-
dc.titleThe Late-Expressed Region of the Temperate Coliphage 186 Genome-
dc.typeJournal article-
dc.identifier.orcidDodd, I. [0000-0003-2969-6841]-
Appears in Collections:Aurora harvest 7
Biochemistry publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.