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https://hdl.handle.net/2440/113886
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dc.contributor.author | Lim, S. | - |
dc.contributor.author | Kortschak, R. | - |
dc.contributor.author | Adelson, D. | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Animal Genetics, 2014; 45(3):367-372 | - |
dc.identifier.issn | 0268-9146 | - |
dc.identifier.issn | 1365-2052 | - |
dc.identifier.uri | http://hdl.handle.net/2440/113886 | - |
dc.description.abstract | Long terminal repeat (LTR) retrotransposons are transposable elements flanked by 5'/3' LTRs. They have a structure similar to endogenous retroviruses, but they lack the envelope (env) gene making them non-infectious. Long terminal repeats are motif-rich sequences and can act as bidirectional promoters or enhancers to regulate or inactivate genes by insertion. In this study, we identified a new chimeric LTR subfamily, LTR2i_SS, in the pig genome. This chimeric LTR family appears to be the ancestral form of the previously described LTR2_SS family. LTR2_SS appears to have deleted ~300 bp of un-annotated, ancestral sequence from LTR2i_SS. We identified no functional provirus sequences for either of these LTR types. LTR2i_SS sequences have been exapted into the untranslated regions of two protein-coding gene mRNAs. Both of these genes lie within previously mapped pig quantitative trait loci. | - |
dc.description.statementofresponsibility | Sim L. Lim, R. Daniel Kortschak and David L. Adelson | - |
dc.language.iso | en | - |
dc.publisher | Wiley | - |
dc.rights | © 2014 Stichting International Foundation for Animal Genetics | - |
dc.source.uri | http://dx.doi.org/10.1111/age.12138 | - |
dc.subject | Exaptation; long terminal repeat; repetitive elements; retrotransposon; retrovirus | - |
dc.title | Discovery of a novel long terminal repeat (LTR2i-SS) in Sus Scrofa | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/age.12138 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Kortschak, R. [0000-0001-8295-2301] | - |
dc.identifier.orcid | Adelson, D. [0000-0003-2404-5636] | - |
Appears in Collections: | Aurora harvest 8 Genetics publications |
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