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PreviewIssue DateTitleAuthor(s)
2014Discovery of a novel site of opioid action at the innate immune pattern-recognition receptor TLR4 and its role in addictionJacobsen, J.; Watkins, L.; Hutchinson, M.
2014Glial TLR4 signaling does not contribute to opioid-induced depression of respirationZwicker, J.; Zhang, Y.; Ren, J.; Hutchinson, M.; Rice, K.; Watkins, L.; Greer, J.; Funk, G.
2015Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced painLewis, S.; Hutchinson, M.; Frick, M.; Zhang, Y.; Maier, S.; Sammakia, T.; Rice, K.; Watkins, L.
2015Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signalingCorrigan, F.; Wu, Y.; Tuke, J.; Coller, J.; Rice, K.; Diener, K.; Hayball, J.; Watkins, L.; Somogyi, A.; Hutchinson, M.
2012Commentary on Landry et al.: "Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages"Watkins, L.; Hutchinson, M.; Johnson, K.
2013Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced painLewis, S.; Hutchinson, M.; Zhang, Y.; Hund, D.; Maier, S.; Rice, K.; Watkins, L.
2012(+)-Naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in ratsLewis, S.; Loram, L.; Hutchinson, M.; Li, C.; Zhang, Y.; Maier, S.; Huang, Y.; Rice, K.; Watkins, L.
2013Effect of chronic delivery of the toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin cravingTheberge, F.; Li, X.; Kambhampati, S.; Pickens, C.; St Laurent, R.; Bossert, J.; Baumann, M.; Hutchinson, M.; Rice, K.; Watkins, L.; Shaham, Y.
2014In vivo veritas: (+)-Naltrexone's actions define translational importance. A letter in response to Skolnick et al. 'Translational potential of naloxone and naltrexone as TLR4 antagonists'Watkins, L.; Wang, X.; Mustafa, S.; Hutchinson, M.