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dc.contributor.authorMunawar, D.en
dc.contributor.authorMahajan, R.en
dc.contributor.authorLinz, D.en
dc.contributor.authorWong, G.en
dc.contributor.authorKhokhar, K.en
dc.contributor.authorThiyagarajah, A.en
dc.contributor.authorKadhim, K.en
dc.contributor.authorEmami, M.en
dc.contributor.authorMishima, R.en
dc.contributor.authorElliott, A.en
dc.contributor.authorMiddeldorp, M.en
dc.contributor.authorRoberts-Thompson, K.en
dc.contributor.authorYoung, G.en
dc.contributor.authorSanders, P.en
dc.contributor.authorLau, D.en
dc.identifier.citationHeart Rhythm, 2018; 15(12):1756-1763en
dc.description.abstractBackground: Battery longevity is an important factor that may influence the selection of cardiac implantable electronic devices (CIEDs). However, there remains a lack of industry-wide standardized reporting of predicted CIED longevity to facilitate informed decision-making for implanting physicians and payers. Objective: The purpose of this study was to compare the predicted longevity of current generation CIEDs using best-matched CIEDs settings to assess differences between brands and models. Methods: Data were extracted for current model pacemakers, implantable cardioverter–defibrillators (ICDs), and cardiac resynchronization therapy–defibrillators (CRT-Ds) from product manuals and, where absent, by communication with the manufacturers. Pacemaker longevity estimations were based on standardized pacing outputs (2.5V, 0.40-ms pulse width, 500-Ω impedance) and pacing loads of 50% or 100% at 60 bpm. ICD and CRT-D longevity were estimated at 0% pacing and 15% atrial plus 100% biventricular pacing, with essential capacitor reforms and zero clinical shocks. Results: Mean maximum predicted longevity of single- and dual-chamber pacemakers was 12.0 ± 2.1 and 9.8 ± 1.9 years, respectively. Use of advanced features such as remote monitoring, prearrhythmia electrogram storage, and rate response can result in ∼1.4 years of reduction in longevity. Mean maximum predicted longevity of ICDs and CRT-Ds was 12.4 ± 3.0 and 8.8 ± 2.1 years, respectively. Of note, there were significant variations in predicted CIED longevity according to device manufacturers, with up to 44%, 42%, and 44% difference for pacemakers, ICDs, and CRT-Ds, respectively. Conclusion: Contemporary CIEDs demonstrate highly variable predicted longevity according to device manufacturers. This may impact on health care costs and long-term clinical outcomes.en
dc.description.statementofresponsibilityDian A. Munawar, Rajiv Mahajan, Dominik Linz, Geoffrey R.Wong, Kashif B.Khokhar, Anand Thiyagarajah, Kadhim Kadhim, Mehrdad Emami, Ricardo Mishima, Adrian D.Elliott, Melissa E.Middeldorp, Kurt C.Roberts-Thompson, Glenn D.Young, Prashanthan Sanders, Dennis H.Lauen
dc.rights© 2018 Heart Rhythm Society. All rights reserved.en
dc.subjectBattery longevity; Cardiac implantable electronic device; Cardiac resynchronization therapy; Implantable cardioverter-defibrillator; Pacemakeren
dc.titlePredicted longevity of contemporary cardiac implantable electronic devices: a call for industry-wide “standardized” reportingen
dc.typeJournal articleen
pubs.library.collectionMedicine publicationsen
dc.identifier.orcidMahajan, R. [0000-0003-3375-5568]en
dc.identifier.orcidLinz, D. [0000-0003-4893-0824]en
dc.identifier.orcidWong, G. [0000-0002-9733-7712]en
dc.identifier.orcidKhokhar, K. [0000-0003-0896-2039]en
dc.identifier.orcidKadhim, K. [0000-0002-8928-0402]en
dc.identifier.orcidEmami, M. [0000-0003-2093-6909]en
dc.identifier.orcidMishima, R. [0000-0001-5163-7130]en
dc.identifier.orcidElliott, A. [0000-0002-5951-4239]en
dc.identifier.orcidMiddeldorp, M. [0000-0002-4106-9771]en
dc.identifier.orcidSanders, P. [0000-0003-3803-8429]en
dc.identifier.orcidLau, D. [0000-0001-7753-1318]en
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