Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/117548
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Type: Journal article
Title: An integrated platform for capture of circulating tumor cells and in situ SERS profiling of membrane proteins through rational spatial organization of multi-functional cyclic RGD nanopatterns
Author: Dong, H.
Yao, D.
Zhou, Q.
Zhang, L.
Tian, Y.
Citation: ChemComm, 2019; 55(12):1730-1733
Publisher: Royal Society of Chemistry
Issue Date: 2019
ISSN: 1359-7345
1364-548X
Statement of
Responsibility: 
Hui Dong, Dazhi Yao, Qi Zhou, Limin Zhang and Yang Tian
Abstract: It is significant to in situ monitor membrane proteins at the singlecell level for understanding the cell function. Herein, an integrated platform was designed and constructed for highly efficient cell capture and in situ sensitive SERS determination of HER2 activity in cells through rational spatial organization of multi-functional cyclic RGD nanopatterns at a disordered mesoporous gold film via electrochemical activation.
Keywords: Cell Line, Tumor; Humans; Gold; Peptides, Cyclic; Receptor, erbB-2; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Spectrum Analysis, Raman; Porosity; Neoplastic Cells, Circulating
Rights: This journal is © The Royal Society of Chemistry 2019
RMID: 0030107427
DOI: 10.1039/C8CC09108K
Appears in Collections:Chemical Engineering publications

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