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Type: Journal article
Title: Use of potentially inappropriate medications in people with dementia in Vietnam and its associated factors
Author: Nguyen, T.
Pham, T.
Vu, H.
Nguyen, T.
Vu, T.
Nguyen, B.
Nguyen, N.
Nguyen, B.
Nguyen, T.
Phan, S.
Nguyen, A.
Pham, T.
Dang, H.
Kalisch-Ellett, L.
Gillam, M.
Pratt, N.
Qiang, S.
Wang, H.
Kanjanarach, T.
Hassali, M.
et al.
Citation: American Journal of Alzheimer's Disease and other Dementias, 2018; 33(7):423-432
Publisher: SAGE Publications
Issue Date: 2018
ISSN: 1533-3175
Statement of
Tuan Anh Nguyen, Thang Pham, Huyen Thi Thanh Vu, Thanh Xuan Nguyen, Trinh Thi Vu ... Nicole Pratt ... et al.
Abstract: This study examined the use of potentially inappropriate medicines that may affect cognition (PIMcog) in people with dementia and its associated factors. Medical records of all outpatients with dementia attending a tertiary hospital in Vietnam between January 1, 2015, and December 31, 2016, were examined. Medicine use was assessed against a list of PIMcog. Variables associated with having a PIMcog were assessed using a multiple logistic regression. Of the 128 patients, 41% used a PIMcog, 39.1% used cholinesterase inhibitors (CEIs) concomitantly with anticholinergics, and 18% used antipsychotics. The number of hospital visits (adjusted odds ratio [OR]: 1.08; 95% confidence interval [CI]: 1.02-1.16) and number of treating specialists (adjusted OR: 0.61; 95% CI: 0.45-0.83) were associated with PIMcog use. This study highlights a high-level use of medicines that can further impair cognition or reduce the effectiveness of CEIs in people with dementia. Efforts to improve quality use of medicines for this population are warranted.
Keywords: Anticholinergics; antipsychotics; dementia; potentially inappropriate medicines; quality use of medicines; sedatives
Rights: © The Author(s) 2018
RMID: 0030112083
DOI: 10.1177/1533317518768999
Grant ID:
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