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https://hdl.handle.net/2440/121557
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dc.contributor.author | Martin, S.A. | - |
dc.contributor.author | Appleton, S.L. | - |
dc.contributor.author | Adams, R.J. | - |
dc.contributor.author | Taylor, A.W. | - |
dc.contributor.author | Vincent, A. | - |
dc.contributor.author | Brook, N.R. | - |
dc.contributor.author | Catcheside, P.G. | - |
dc.contributor.author | Vakulin, A. | - |
dc.contributor.author | McEvoy, R.D. | - |
dc.contributor.author | Antic, N.A. | - |
dc.contributor.author | Wittert, G.A. | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | Sleep Health, 2017; 3(4):250-256 | - |
dc.identifier.issn | 2352-7218 | - |
dc.identifier.issn | 2352-7218 | - |
dc.identifier.uri | http://hdl.handle.net/2440/121557 | - |
dc.description.abstract | To examine the association between obstructive sleep apnea (OSA) and other sleep indices using polysomnography (PSG) data and erectile dysfunction (ED) in a representative cohort of men.Cross-sectional.Community-based.Aged 40+ years (n=734; mean age [SD], 60.8 [10.9]).Men with no prior OSA diagnosis who underwent in-home PSG (Embletta X100; 2010-11) and ED assessment (Global Impotence Rating) were selected. Un-adjusted and multi-adjusted regression models of ED were fitted against PSG measures, along with qualifying sociodemographic, lifestyle, and health-related covariates. Mediation effects were examined using the Baron-Kenny method.Of the men examined, 24.7% (n=181) had ED, most notably in men older than 65years (cf. men 35-49 and 50-64years; P<.001). There was no significant association between ED and any of the PSG measures for allaged men. Given an observed ageinteraction within OSA categories (P=.005), analyses were repeated in age-stratified samples (<65 years; 65+ years). In men younger than 65years, only severe OSA was found to have an association with ED (2.01; 1.13-4.69) in unadjusted models. For men aged 65+ years, an independent association with ED was found for apnea-hyponea index (AHI; 1.55;1.02-2.36), moderate (AHI:10.0-19.9; 1.79;1.18-2.43), and severe (AHI:20.0+; 4.84;2.56-9.93) OSA, and oxygen desaturation index (ODI; both continuous [1.48;1.03-1.99] and >16 seconds [2.79;1.23-6.32]). The effect of AHI on ED was shown to be primarily mediated through ODI (63.4%, Sobel P value=.29).In younger, community-based men, there appeared no independent relationship between objective measures of sleep and ED. However, there appears a strong, independent relationship between OSA, ODI, and ED in men 65 years and older. | - |
dc.description.statementofresponsibility | Sean A. Martin, Sarah L. Appleton, Robert J. Adams, AnneW. Taylor, Andrew Vincent, Nicholas R. Brook, Peter G. Catcheside, Andrew Vakulin, Douglas McEvoy, Nick A. Antic, Gary A. Wittert | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.rights | © 2017 National Sleep Foundation. Published by Elsevier Inc. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.sleh.2017.04.006 | - |
dc.subject | Humans | - |
dc.subject | Sleep Apnea, Obstructive | - |
dc.subject | Oxygen | - |
dc.subject | Polysomnography | - |
dc.subject | Severity of Illness Index | - |
dc.subject | Risk Factors | - |
dc.subject | Cohort Studies | - |
dc.subject | Cross-Sectional Studies | - |
dc.subject | Age Factors | - |
dc.subject | Middle Aged | - |
dc.subject | Male | - |
dc.subject | Erectile Dysfunction | - |
dc.subject | Independent Living | - |
dc.title | Erectile dysfunction is independently associated with apnea-hypopnea index and oxygen desaturation index in elderly, but not younger, community-dwelling men | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.sleh.2017.04.006 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/627227 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Appleton, S.L. [0000-0001-7292-9714] | - |
dc.identifier.orcid | Adams, R.J. [0000-0002-7572-0796] | - |
dc.identifier.orcid | Taylor, A.W. [0000-0002-4422-7974] | - |
dc.identifier.orcid | Vincent, A. [0000-0002-6428-1070] | - |
dc.identifier.orcid | Catcheside, P.G. [0000-0002-9372-6788] | - |
dc.identifier.orcid | McEvoy, R.D. [0000-0002-5759-0094] | - |
dc.identifier.orcid | Wittert, G.A. [0000-0001-6818-6065] | - |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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