Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/128730
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Association of poor postnatal growth with neurodevelopmental impairment in infancy and childhood: comparing the fetus and the healthy preterm infant references |
Author: | Cordova, E.G. Cherkerzian, S. Bell, K. Joung, K.E. Collins, C.T. Makrides, M. Gould, J. Anderson, P.J. Belfort, M.B. |
Citation: | Journal of Pediatrics, 2020; 225:37-45 |
Publisher: | Elsevier |
Issue Date: | 2020 |
ISSN: | 0022-3476 1097-6833 |
Statement of Responsibility: | Erika G. Cordova, Sara Cherkerzian, Katherine Bell, Kyoung Eun Joung, Carmel T.Collins, Maria Makrides, Jacqueline Gould, Peter J. Anderson, Mandy Brown Belfort |
Abstract: | OBJECTIVES: To compare the classification of preterm postnatal poor growth using healthy-preterm versus fetal growth references and to examine associations with neurodevelopmental impairment in infancy and childhood. STUDY DESIGN: We included 613 infants born at <33 weeks of gestation. Using the INTERGROWTH-21st (healthy-preterm growth) reference and the Fenton and Olsen (fetal growth) references, we classified poor growth as a decline in z-score from birth to term-equivalent >0.8 SD (weight), >1 SD (head), and >2 SD (length). We used generalized estimating equations to estimate odds ratios (aOR) for neurodevelopmental impairment at 18 months and 7 years of corrected age, comparing infants with and without poor growth by each reference, accounting for multiple births and covariates. RESULTS: The prevalence of poor growth was higher with INTERGROWTH-21st than with fetal references for all measurements. Agreement was higher between the Fenton and Olsen (fetal) growth references (0.72-0.81) than between INTERGROWTH-21st and fetal references (0.41-0.59). Poor growth by fetal references (but not by INTERGROWTH-21st) was associated with low neurodevelopmental scores in infancy and childhood. Poor weight gain using the Fenton reference was associated with 18-month Mental Developmental Index <85 (aOR 1.6, 95%CI: 1.1, 2.4) whereas poor weight gain by the INTERGROWTH-21st reference was not (aOR 1.0, 95%CI: 0.6, 1.7). Poor linear growth by the Olsen reference, but not INTERGROWTH-21st, was associated with 7-year verbal intelligence quotient <70 (aOR 3.5, 95%CI: 1.1, 12.7). CONCLUSIONS: Poor neonatal growth categorized using fetal references showed stronger associations with long term neurodevelopment than poor growth categorized using the INTERGROWTH-21st standards. |
Keywords: | Fetus Humans Infant, Newborn, Diseases Birth Weight Docosahexaenoic Acids Prevalence Data Interpretation, Statistical Fetal Development Gestational Age Reference Values Child Child, Preschool Infant Infant, Newborn Infant, Premature India Turkey Female Male Growth Charts Neurodevelopmental Disorders |
Rights: | © 2020 Elsevier Inc. All rights reserved. |
DOI: | 10.1016/j.jpeds.2020.05.063 |
Published version: | http://dx.doi.org/10.1016/j.jpeds.2020.05.063 |
Appears in Collections: | Aurora harvest 8 Paediatrics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.