Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/131071
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gebremichael, L.G. | - |
dc.contributor.author | Suppiah, V. | - |
dc.contributor.author | Wiese, M.D. | - |
dc.contributor.author | Mackenzie, L. | - |
dc.contributor.author | Phillips, C. | - |
dc.contributor.author | Williams, D.B. | - |
dc.contributor.author | Roberts, M.S. | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Pharmacogenomics, 2021; 22(9):553-571 | - |
dc.identifier.issn | 1462-2416 | - |
dc.identifier.issn | 1744-8042 | - |
dc.identifier.uri | http://hdl.handle.net/2440/131071 | - |
dc.description.abstract | Although statins are effective in treating high cholesterol, adverse effects do occur with their use. Efficacy and tolerability vary among statins in different ethnic groups. Indigenous Australians have a high risk for cardiovascular and kidney diseases. Prescribing statins to Indigenous Australians with multi-morbidity requires different strategies to increase efficacy and reduce their toxicity. Previous studies have reported that Indigenous Australians are more susceptible to severe statin-induced myopathies. However, there is a lack of evidence in the underlying genetic factors in this population. This review aims to identify: inter-ethnic differences in the efficacy and safety of statins; major contributing factors accounting for any identified differences; and provide an overview of statin-induced adverse effects in Indigenous Australians. | - |
dc.description.statementofresponsibility | Lemlem G Gebremichael, Vijayaprakash Suppiah, Michael D Wiese, Lorraine Mackenzie, Craig Phillips, Desmond B Williams, Michael S Roberts | - |
dc.language.iso | en | - |
dc.publisher | Future Medicine | - |
dc.rights | © 2021 Future Medicine Ltd. | - |
dc.source.uri | http://dx.doi.org/10.2217/pgs-2020-0152 | - |
dc.subject | Indigenous | - |
dc.subject | ethnic groups | - |
dc.subject | pharmacogenetics | - |
dc.subject | safety | - |
dc.subject | statin | - |
dc.title | Efficacy and safety of statins in ethnic differences: a lesson for application in Indigenous Australian patient care | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.2217/pgs-2020-0152 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/1107356 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Suppiah, V. [0000-0001-5496-935X] | - |
Appears in Collections: | Aurora harvest 8 Biochemistry publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.