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Type: Journal article
Title: Comparative antibacterial activity of 2D materials coated on the porous-titania
Author: Mazinani, A.
Rastin, H.
Nine, M.J.
Lee, J.
Tikhomirova, A.
Tung, T.T.
Ghomashchi, R.
Kidd, S.P.
Vreugde, S.
Losic, D.
Citation: Journal of Materials Chemistry B, 2021; 32(32):6412-6424
Publisher: Royal Society of Chemistry
Issue Date: 2021
ISSN: 2050-750X
Statement of
Arash Mazinani, Hadi Rastin, Md Julker Nine, James Lee, Alexandra Tikhomirova, Tran Thanh Tung ... et al.
Abstract: Plasma electrolytic oxidation (PEO) is a well-established technique for the treatment of titanium-based materials. The formed titania-PEO surface can improve the osseointegration properties of titanium implants. Nevertheless, it can not address bacterial infection problems associated with bone implants. Recently, 2-dimensional (2D) materials such as graphene oxide (GO), MXene, and hexagonal boron nitride (hBN) have received considerable attention for surface modifications showing their antibacterial properties. In this paper, a comparative study on the effect of partial deposition of these three materials over PEO titania substrates on the antibacterial efficiency and bioactivity is presented. Their partial deposition through drop-casting instead of continuous film coating is propsed to simultaneously address both antibacterial and osseointegration abilities. Our results demonstrate the dose-dependent nature of the deposited antibacterial agent on the PEO substrate. GO–PEO and MXene–PEO samples showed the highest antibacterial activity with 70 (±2) % and 97 (±0.5) % inactivation of S. aureus colonies in the low concentration group, respectively. Furthermore, only samples in the higher concentration group were effective against E. coli bacteria with 18 (±2) % and 17 (±4) % decrease in numbers of colonies for hBN–PEO and GO–PEO samples, respectively. Moreover, all antibacterial samples demonstrated acceptable bioactivity and good biocompatibility, making them a considerable candidates for the next generation of antibacterial titanium implants.
Keywords: Escherichia coli
Staphylococcus aureus
Boron Compounds
Coated Materials, Biocompatible
Anti-Bacterial Agents
Prostheses and Implants
Surface Properties
Rights: This journal is © The Royal Society of Chemistry 2021
DOI: 10.1039/d1tb01122g
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Appears in Collections:ARC Research Hub for Graphene Enabled Industry Transformation publications
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