Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/138396
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Type: | Journal article |
Title: | Dynamic axial control over optically levitating particles in air with an electrically-tunable variable-focus lens |
Author: | Zhu, W. Eckerskorn, N. Upadhya, A. Li, L. Rode, A.V. Lee, W.M. |
Citation: | Biomedical Optics Express, 2016; 7(7):2902-2911 |
Publisher: | Optical Society of America |
Issue Date: | 2016 |
ISSN: | 2156-7085 2156-7085 |
Statement of Responsibility: | Wenguo Zhu, Niko Eckerskorn, Avinash Upadhya, Li Li, Andrei V. Rode, and Woei Ming Lee |
Abstract: | Efficient delivery of viruses, proteins and biological macromelecules into a micrometer-sized focal spot of an XFEL beam for coherent diffraction imaging inspired new development in touch-free particle injection methods in gaseous and vacuum environments. This paper lays out our ongoing effort in constructing an all-optical particle delivery approach that uses piconewton photophoretic and femtonewton light-pressure forces to control particle delivery into the XFEL beam. We combine a spatial light modulator (SLM) and an electrically tunable lens (ETL) to construct a variable-divergence vortex beam providing dynamic and stable positioning of levitated micrometer-size particles, under normal atmospheric pressure. A sensorless wavefront correction approach is used to reduce optical aberrations to generate a high quality vortex beam for particle manipulation. As a proof of concept, stable manipulation of optically-controlled axial motion of trapped particles is demonstrated with a response time of 100ms. In addition, modulation of trapping intensity provides a measure of the mass of a single, isolated particle. The driving signal of this oscillatory motion can potentially be phase-locked to an external timing signal enabling synchronization of particle delivery into the x-ray focus with XFEL pulse train. |
Keywords: | (140.7010) Laser trapping (350.4855) Optical tweezers or optical manipulation |
Rights: | ©2016 Optical Society of America. Open Access (CC BY 4.0) |
DOI: | 10.1364/BOE.7.002902 |
Grant ID: | http://purl.org/au-research/grants/arc/DP110100975 http://purl.org/au-research/grants/arc/DE160100843 |
Published version: | http://dx.doi.org/10.1364/boe.7.002902 |
Appears in Collections: | Biochemistry publications |
Files in This Item:
File | Description | Size | Format | |
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hdl_138396.pdf | Published version | 3 MB | Adobe PDF | View/Open |
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