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PreviewIssue DateTitleAuthor(s)
2007CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomesDavies, B.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2007Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemiaInglis, S.; Herbert, M.; Davies, B.; Coller, J.; James, H.; Horowitz, J.; Morris, R.; Milne, R.; Somogyi, A.; Sallustio, B.
2008Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexilineDavies, B.; Herbert, M.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2005The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemiaDavies, B.; Coller, J.; James, H.; Somogyi, A.; Horowitz, J.; Sallustio, B.
2006Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatographyDavies, B.; Herbert, M.; Culbert, J.; Pyke, S.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2006Determination of the 4-monohydroxy metabolites of perhexiline in human plasma, urine and liver microsomes by liquid chromatographyDavies, B.; Herbert, M.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2003Relationship between CYP2D6 genotype and plasma OH-perhexiline/perhexiline concentration ratio in angina patients.Sallustio, B.; Davies, B.; Coller, J.; James, H.; Gillis, D.; Somogyi, A.
2004Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexilineDavies, B.; Coller, J.; James, H.; Gillis, D.; Somogyi, A.; Horowitz, J.; Morris, R.; Sallustio, B.
2004A new simple diagnostic assay for the identification of the major CYP2D6 genotypes by DNA sequencing analysisJames, H.; Coller, J.; Gillis, D.; Bahnisch, J.; Sallustio, B.; Somogyi, A.