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Results 1-10 of 13 (Search time: 0.002 seconds).
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PreviewIssue DateTitleAuthor(s)
2004A new simple diagnostic assay for the identification of the major CYP2D6 genotypes by DNA sequencing analysisJames, H.; Coller, J.; Gillis, D.; Bahnisch, J.; Sallustio, B.; Somogyi, A.
2007Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: Role of acyl glucuronide metabolites and glycation pathwaysSouthwood, H.; DeGraaf, Y.; MacKenzie, P.; Miners, J.; Burcham, P.; Sallustio, B.
2004Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7Toutsikos, P.; Miners, J.; Stapleton, A.; Thomas, A.; Sallustio, B.; Knights, K.
2005Validation of a high-performance liquid chromatography method for the measurement of mycophenolic acid and its glucuronide metabolites in plasmaWestley, I.; Sallustio, B.; Morris, R.
2008Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexilineDavies, B.; Herbert, M.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2007Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemiaInglis, S.; Herbert, M.; Davies, B.; Coller, J.; James, H.; Horowitz, J.; Morris, R.; Milne, R.; Somogyi, A.; Sallustio, B.
2004Optimisation of the comet genotoxicity assay in freshly isolated murine hepatocytes: detection of strong in vitro DNA damaging properties for styreneFontaine, F.; DeGraaf, Y.; Ghaoui, R.; Sallustio, B.; Edwards, J.; Burcham, P.
2005Evaluation of the immunotech cyclosporine direct radioimmunoassay for the determination of whole-blood cyclosporine in renal transplant patientsWesley, I.; Sallustio, B.; Morris, R.
2004Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexilineDavies, B.; Coller, J.; James, H.; Gillis, D.; Somogyi, A.; Horowitz, J.; Morris, R.; Sallustio, B.
2002Pharmacokinetics of the antianginal agent perhexiline: relationship between metabolic ratio and steady-state doseSallustio, B.; Westley, I.; Morris, R.