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Issue Date
Title
Author(s)
2001
In vivo perturbation of rat hepatocyte canalicular membrane function by diclofenac
Sallustio, B.
;
Holbrook, F.
2004
A new simple diagnostic assay for the identification of the major CYP2D6 genotypes by DNA sequencing analysis
James, H.
;
Coller, J.
;
Gillis, D.
;
Bahnisch, J.
;
Sallustio, B.
;
Somogyi, A.
2003
Relationship between CYP2D6 genotype and plasma OH-perhexiline/perhexiline concentration ratio in angina patients.
Sallustio, B.
;
Davies, B.
;
Coller, J.
;
James, H.
;
Gillis, D.
;
Somogyi, A.
2000
Hepatic disposition of the acyl glucoronide 1-O-gemfibrozil--D-glucoronide: Effects of clofibric acid, acetaminophen, and acetaminophen glucuronide
Sabordo, L.
;
Sallustio, B.
;
Evans, A.
;
Nation, R.
2007
Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: Role of acyl glucuronide metabolites and glycation pathways
Southwood, H.
;
DeGraaf, Y.
;
MacKenzie, P.
;
Miners, J.
;
Burcham, P.
;
Sallustio, B.
2004
Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7
Toutsikos, P.
;
Miners, J.
;
Stapleton, A.
;
Thomas, A.
;
Sallustio, B.
;
Knights, K.
2005
Validation of a high-performance liquid chromatography method for the measurement of mycophenolic acid and its glucuronide metabolites in plasma
Westley, I.
;
Sallustio, B.
;
Morris, R.
2008
Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline
Davies, B.
;
Herbert, M.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2005
The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemia
Davies, B.
;
Coller, J.
;
James, H.
;
Somogyi, A.
;
Horowitz, J.
;
Sallustio, B.
2007
Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia
Inglis, S.
;
Herbert, M.
;
Davies, B.
;
Coller, J.
;
James, H.
;
Horowitz, J.
;
Morris, R.
;
Milne, R.
;
Somogyi, A.
;
Sallustio, B.
Discover
Author
9
Coller, J.
9
Somogyi, A.
8
Davies, B.
8
Morris, R.
5
James, H.
5
Milne, R.
4
Burcham, P.
4
Evans, A.
4
Herbert, M.
4
Westley, I.
.
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Subject
3
Liver
3
Metabolic Clearance Rate
3
Mice
3
Microsomes, Liver
3
Mycophenolic Acid
3
perhexiline
3
Phenotype
3
Reproducibility of Results
3
Stereoisomerism
2
Aged, 80 and over
.
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