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Results 11-20 of 41 (Search time: 0.002 seconds).
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PreviewIssue DateTitleAuthor(s)
2004A new simple diagnostic assay for the identification of the major CYP2D6 genotypes by DNA sequencing analysisJames, H.; Coller, J.; Gillis, D.; Bahnisch, J.; Sallustio, B.; Somogyi, A.
2008Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexilineDavies, B.; Herbert, M.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2003Relationship between CYP2D6 genotype and plasma OH-perhexiline/perhexiline concentration ratio in angina patients.Sallustio, B.; Davies, B.; Coller, J.; James, H.; Gillis, D.; Somogyi, A.
2007Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemiaInglis, S.; Herbert, M.; Davies, B.; Coller, J.; James, H.; Horowitz, J.; Morris, R.; Milne, R.; Somogyi, A.; Sallustio, B.
2007CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomesDavies, B.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2014Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptakeDrury, N.; Licari, G.; Chong, C.; Howell, N.; Frenneaux, M.; Horowitz, J.; Pagano, D.; Sallustio, B.
2015Comparison of CYP2D metabolism and hepatotoxicity of the myocardial metabolic agent perhexiline in Sprague-Dawley and Dark Agouti ratsLicari, G.; Somogyi, A.; Milne, R.; Sallustio, B.
2007Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: Role of acyl glucuronide metabolites and glycation pathwaysSouthwood, H.; DeGraaf, Y.; MacKenzie, P.; Miners, J.; Burcham, P.; Sallustio, B.
2000In vitro covalent binding of Nafenopin-CoA to human liver proteinsSallustio, B.; Nunthasomboon, S.; Drogemuller, C.; Knights, K.
2006Bioactivation of carboxylic acid compounds by UDP-glucuronosyltransferases to DNA-damaging intermediates: Role of glycoxidation and oxidative stress in genotoxicitySallustio, B.; DeGraaf, Y.; Weekley, J.; Burcham, P.