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PreviewIssue DateTitleAuthor(s)
2004Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexilineDavies, B.; Coller, J.; James, H.; Gillis, D.; Somogyi, A.; Horowitz, J.; Morris, R.; Sallustio, B.
2004Optimisation of the comet genotoxicity assay in freshly isolated murine hepatocytes: detection of strong in vitro DNA damaging properties for styreneFontaine, F.; DeGraaf, Y.; Ghaoui, R.; Sallustio, B.; Edwards, J.; Burcham, P.
2005The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemiaDavies, B.; Coller, J.; James, H.; Somogyi, A.; Horowitz, J.; Sallustio, B.
2013Validation of an LC-MS/MS method to measure tacrolimus in rat kidney and liver tissue and its application to human kidney biopsiesNoll, B.; Coller, J.; Somogyi, A.; Morris, R.; Russ, G.; Hesselink, D.; van Gelder, T.; Sallustio, B.
2006Bioactivation of carboxylic acid compounds by UDP-glucuronosyltransferases to DNA-damaging intermediates: Role of glycoxidation and oxidative stress in genotoxicitySallustio, B.; DeGraaf, Y.; Weekley, J.; Burcham, P.
2004Determination of perhexiline and hydroxyperhexiline in plasma by liquid chromatography-mass spectrometryBeck, O.; Stephanson, N.; Morris, R.; Sallustio, B.; Hjemdahl, P.
2014Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptakeDrury, N.; Licari, G.; Chong, C.; Howell, N.; Frenneaux, M.; Horowitz, J.; Pagano, D.; Sallustio, B.
1997Effects of gemfribozil and clofibric acid on the uptake of taurocholate by isolated rat hepatocytesSabordo, L.; Sallustio, B.
1999Hepatic disposition of the acyl glucuronide1-0-gemfibrozil-β-D-glucuronide effects of dibromosulfophthalein in membrane transport and aglycone formationSabordo, L.; Sallustio, B.; Evans, A.; Nation, R.
2007CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomesDavies, B.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.