Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/14270
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Type: Journal article
Title: A review of biological indicators of illicit drug use, practical considerations and clinical usefulness.
Author: Wolff, K.
Farrell, M.
Marsden, J.
Monteiro, M.
Ali, R.
Welch, S.
Strang, J.
Citation: Addiction, 1999; 94(9):1279-1298
Publisher: WILEY
Issue Date: 1999
ISSN: 0965-2140
1360-0443
Statement of
Responsibility: 
K. Wolff, M. Farrell, J. Marsden, M. G. Monteiro, R. Ali, S. Welch, J. Strang
Abstract: AIMS:To examine a range of biological indicators of illicit drug use, including blood, urine, hair and saliva, addressing both technological and practical issues relating to their application and interpretation. METHODS:The review process involved an examination of key reference texts and literature from the scientific fields of analytical and clinical toxicology. FINDINGS:Urine remains the biological tool of choice for qualitative detection of illicit drug use in a clinical setting, while quantitative accuracy remains strictly the domain of blood. The growing sophistication of laboratory analysis may additionally make possible the routine use of hair sampling which can provide a much longer time frame for assessment. Breath, saliva, sweat or breast milk remain possibilities in the future. CONCLUSIONS:Accurate interpretation of the screening tests within a clinical setting alongside other relevant information remains the key to the usefulness of any test.
Keywords: Humans; Substance-Related Disorders; Health Status Indicators; Substance Abuse Detection; Biomarkers
RMID: 0030003453
DOI: 10.1046/j.1360-0443.1999.94912792.x
Appears in Collections:Pharmacology publications

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