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https://hdl.handle.net/2440/14736
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Type: | Journal article |
Title: | Cardiovascular and haemodynamic effects of intramuscular doses of xylazine in conscious sheep |
Author: | Grant, C. Upton, R. |
Citation: | Australian Veterinary Journal, 2001; 79(1):58-60 |
Publisher: | Australian Veterinary Assn |
Issue Date: | 2001 |
ISSN: | 0005-0423 1751-0813 |
Abstract: | OBJECTIVE: To determine if a commonly used analgesic dose of xylazine has detrimental cardiovascular or haemodynamic effects in sheep. DESIGN: A physiological study following intramuscular administration of xylazine. PROCEDURE: Xylazine (50 micrograms/kg) was injected intramuscularly into six healthy Merino ewes. For 60 min heart rate, mean arterial blood pressure and cardiac output were recorded; arterial blood samples for the measurement of blood gas tensions were also collected. RESULTS: There were no significant changes in heart rate, mean arterial blood pressure, cardiac output or arterial carbon dioxide tension. A slight degree of arterial hypoxaemia was noted with a 10% reduction in arterial oxygen tension values at 30 min. CONCLUSION: The minimal changes to cardiovascular and respiratory values in this study verify the safety of previously suggested analgesic dosing regimens for sheep. Previously reported hypoxaemic effects in sheep as a result of intravenous xylazine administration appear to be reduced as a result of intramuscular administration. |
Keywords: | Sheep analgesia xylazine hypoxaemia |
DOI: | 10.1111/j.1751-0813.2001.tb10642.x |
Published version: | http://dx.doi.org/10.1111/j.1751-0813.2001.tb10642.x |
Appears in Collections: | Anaesthesia and Intensive Care publications Aurora harvest 7 |
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