Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/17698
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Type: Journal article
Title: Correlation of postmortem MRI and CT appearances with neuropathology in brain trauma: a comparison of two methods
Author: Jones, N.
Blumbergs, P.
Brown, C.
McLean, J.
Manavis, J.
Perrett, L.
Sandhu, A.
Scott, G.
Simpson, D.
Citation: Journal of Clinical Neuroscience, 1998; 5(1):73-79
Publisher: CHURCHILL LIVINGSTONE
Issue Date: 1998
ISSN: 0967-5868
1532-2653
Statement of
Responsibility: 
Nigel R Jones, Peter C Blumbergs, Christopher J Brown, A.Jack McLean, James Manavis, Lance V Perrett, Avinder Sandhu, Grace Scott, Donald A Simpson
Abstract: Postmortem magnetic resonance (MR) scans were performed on the brains of 12 victims of fatal head injuries. These were compared with neuropathological studies of the entire brain. The first six subjects were imaged with the brain in situ and comparison was also made with antemortem computed tomography (CT). The brains from the subsequent six subjects were removed at autopsy, fixed in formalin and then imaged in a mitre box designed to overcome the problems encountered in the pilot study. Although both CT and MR imaging (MRI) detected all clinically relevant haemorrhagic lesions, many pathologically significant lesions were missed. MRI detected many more lesions than CT, but still failed to visualize areas of non-haemorrhagic axonal injury.
Keywords: head injury; MRI; CT; neuropathology; axonal injury
Rights: Copyright © 1988 Published by Elsevier Ltd.
RMID: 0030003222
DOI: 10.1016/S0967-5868(98)90207-7
Appears in Collections:Centre for Automotive Safety Research publications

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