1. Adelaide Research & Scholarship
  2. Schools and Disciplines
  3. School of Chemistry and Physics
  4. Chemistry
  5. Chemistry publications
Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/17797
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAnderson, R.-
dc.contributor.authorHill, J.-
dc.contributor.authorMorris, J.-
dc.date.issued2005-
dc.identifier.citationJournal of Organic Chemistry, 2005; 70(16):6204-6212-
dc.identifier.issn0022-3263-
dc.identifier.issn1520-6904-
dc.identifier.urihttp://hdl.handle.net/2440/17797-
dc.description.abstractThe total synthesis of the marine alkaloid variolin B has been achieved in 8 steps and 17% overall yield, starting from commercially available 4-chloro-2-methylthiopyrimidine. The key reaction involves the tandem deoxygenation and cyclization of a triarylmethanol using a combination of triethylsilane and trifluoroacetic acid. In addition, the deoxygenated analogue was prepared in 6 steps and 23% overall yield, starting from the same starting material.-
dc.description.statementofresponsibilityRegan J. Anderson, Jonathan B. Hill, and Jonathan C. Morris-
dc.language.isoen-
dc.publisherAmer Chemical Soc-
dc.rights© 2005 American Chemical Society-
dc.source.urihttp://pubs.acs.org/cgi-bin/abstract.cgi/joceah/2005/70/i16/abs/jo050523v.html-
dc.subjectOxygen-
dc.subjectAza Compounds-
dc.subjectTrifluoroacetic Acid-
dc.subjectPyrimidines-
dc.subjectMolecular Structure-
dc.subjectCyclization-
dc.titleConcise total syntheses of variolin B and deoxyvariolin B-
dc.typeJournal article-
dc.identifier.doi10.1021/jo050523v-
pubs.publication-statusPublished-
Appears in Collections:Aurora harvest 6
Chemistry publications

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.