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Type: Journal article
Title: Coexistent chronic conditions and asthma quality of life - A population-based study
Author: Adams, R.
Wilson, D.
Taylor, A.
Daly, A.
Tursan d'Espaignet, E.
DalGrande, E.
Ruffin, R.
Citation: Chest, 2006; 129(2):285-291
Publisher: Amer Coll Chest Physicians
Issue Date: 2006
ISSN: 0012-3692
Statement of
Robert J. Adams, David H. Wilson, Anne W. Taylor, Alison Daly, Edouard Tursan d’Espaignet, Eleonora Dal Grande, and Richard E. Ruffin
Abstract: OBJECTIVE: Reports of the prevalence and impact of comorbid conditions among people with asthma have been limited to certain population groups or convenience samples. Our aim was to examine the prevalence of major comorbidity in asthma and associations with quality of life and functional status in the general population. STUDY DESIGN/SETTING: The WANTS Health and Well-being Survey is a cross-sectional representative population household telephone interview survey in three Australian states. PARTICIPANTS: Representative sample of noninstitutionalized adults in three Australian states. MEASUREMENT AND RESULTS: From the available sample of 10,080 patients, 7,619 interviews were completed (participation rate, 74.8%), with 834 people reporting current doctor-diagnosed asthma (11.2%). People with asthma were more likely to report one of the selected comorbid conditions: diabetes, arthritis, heart disease, stroke, cancer, osteoporosis (adjusted odds ratio, 1.9; 95% confidence interval, 1.5 to 2.2). Among people with asthma, there were statistically and clinically significant decreases in usual activity levels and in Short Form-12 physical component summary scores when another chronic condition was also present. For those with any of the chronic conditions, the additional presence of asthma was associated with significant further impairment in quality of life in those aged > 35 years but not in younger adults. CONCLUSION: The significant reduction in quality of life associated with comorbidity in asthma has implications for disease management and organization of care, as well as for the design and external validity of single-disease clinical trials.
Keywords: Asthma; comorbidity; population study; quality of life
Description: © American College of Chest Physicians
RMID: 0020060066
DOI: 10.1378/chest.129.2.285
Appears in Collections:Medicine publications

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