Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/23847
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | DeBolt, S. | - |
dc.contributor.author | Cook, D. | - |
dc.contributor.author | Ford, C. | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Proceedings of the National Academy of Sciences of USA, 2006; 103(14):5608-5613 | - |
dc.identifier.issn | 0027-8424 | - |
dc.identifier.issn | 1091-6490 | - |
dc.identifier.uri | http://hdl.handle.net/2440/23847 | - |
dc.description | © 2006 by The National Academy of Sciences of the USA | - |
dc.description.abstract | The biosynthetic pathway of L-tartaric acid, the form most commonly encountered in nature, and its catabolic ties to vitamin C, remain a challenge to plant scientists. Vitamin C and L-tartaric acid are plant-derived metabolites with intrinsic human value. In contrast to most fruits during development, grapes accumulate L-tartaric acid, which remains within the berry throughout ripening. Berry taste and the organoleptic properties and aging potential of wines are intimately linked to levels of L-tartaric acid present in the fruit, and those added during vinification. Elucidation of the reactions relating L-tartaric acid to vitamin C catabolism in the Vitaceae showed that they proceed via the oxidation of L-idonic acid, the proposed rate-limiting step in the pathway. Here we report the use of transcript and metabolite profiling to identify candidate cDNAs from genes expressed at developmental times and in tissues appropriate for L-tartaric acid biosynthesis in grape berries. Enzymological analyses of one candidate confirmed its activity in the proposed rate-limiting step of the direct pathway from vitamin C to tartaric acid in higher plants. Surveying organic acid content in Vitis and related genera, we have identified a non-tartrate-forming species in which this gene is deleted. This species accumulates in excess of three times the levels of vitamin C than comparably ripe berries of tartrate-accumulating species, suggesting that modulation of tartaric acid biosynthesis may provide a rational basis for the production of grapes rich in vitamin C. | - |
dc.description.statementofresponsibility | Seth DeBolt, Douglas R. Cook, and Christopher M. Ford | - |
dc.language.iso | en | - |
dc.publisher | Natl Acad Sciences | - |
dc.source.uri | http://www.pnas.org/cgi/content/full/103/14/5608 | - |
dc.subject | Idonate dehydrogenase | - |
dc.subject | transcriptional profiling | - |
dc.subject | organic acid | - |
dc.subject | biosynthesis | - |
dc.subject | Vitis vinifera | - |
dc.title | L-Tartaric acid synthesis from vitamin C in higher plants | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1073/pnas.0510864103 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Ford, C. [0000-0003-1617-2977] | - |
Appears in Collections: | Agriculture, Food and Wine publications Aurora harvest 2 |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.