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https://hdl.handle.net/2440/29
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Type: | Journal article |
Title: | Isolation and characterization of a novel venom protein from an endoparasitoid, Cotesia rubecula (Hym : Braconidae) |
Author: | Asgari, S. Zareie, R. Zhang, G. Schmidt, O. |
Citation: | Archives of Insect Biochemistry and Physiology, 2003; 53(2):92-100 |
Publisher: | Wiley-Liss |
Issue Date: | 2003 |
ISSN: | 0739-4462 1520-6327 |
Statement of Responsibility: | Sassan Asgari, Reza Zareie, Guangmei Zhang, Otto Schmidt |
Abstract: | <jats:title>Abstract</jats:title><jats:p>Insects are important vectors of diseases with remarkable immune defense capabilities. Hymenopteran endoparasitoids are adapted to overcome the host defense system and, therefore, are useful sources of immune‐suppressing proteins. Not much is known about venom proteins in endoparasitoids, especially those that have a functional relationship with polydnaviruses (PDVs). Here, we describe the isolation and characterization of a small venom protein (Vn4.6) from an endoparasitoid, <jats:italic>Cotesia rubecula</jats:italic>, which interferes with the activation of the host hemolymph prophenoloxidase. The coding region for Vn4.6 is located upstream in the opposite direction of a gene coding for a <jats:italic>C. rubecula</jats:italic> PDV‐protein (Crp32). Arch. Insect Biochem. Physiol. 53:92–100, 2003. © 2003 Wiley‐Liss, Inc.</jats:p> |
Keywords: | Cotesia rubecula venom prophenoloxidase protease inhibitor |
Description: | The definitive version may be found at www.wiley.com |
DOI: | 10.1002/arch.10088 |
Published version: | http://dx.doi.org/10.1002/arch.10088 |
Appears in Collections: | Agriculture, Food and Wine publications Aurora harvest 6 |
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