Adelaide Research & Scholarship
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https://hdl.handle.net/2440/34862
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| Type: | Journal article |
| Title: | Synthesis of functionalized piperidinones |
| Author: | Humphries, M. Murphy, J. Phillips, A. Abell, A. |
| Citation: | Journal of Organic Chemistry, 2003; 68(6):2432-2436 |
| Publisher: | Amer Chemical Soc |
| Issue Date: | 2003 |
| ISSN: | 0022-3263 1520-6904 |
| Statement of Responsibility: | Mark E. Humphries, James Murphy, Andrew J. Phillips, and Andrew D. Abell |
| Abstract: | A versatile, stereoselective synthesis of 5-hydroxypiperidinones with substituents at N1, C3, and C6 has been developed. The sequence involves ring-closing metathesis of a diene amide and epoxidation of the resulting alkene, followed by base-mediated elimination, and finally hydrogenation. |
| Description: | Copyright © 2003 American Chemical Society |
| DOI: | 10.1021/jo0267091 |
| Published version: | http://pubs.acs.org/cgi-bin/abstract.cgi/joceah/2003/68/i06/abs/jo0267091.html |
| Appears in Collections: | Aurora harvest 6 Chemistry publications |
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