Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/35677
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Long-standing type II diabetes mellitus is not a risk factor for slow gastric emptying in critically ill patients |
Author: | Nguyen, Q. Chapman, M. Fraser, R. Ritz, M. Bryant, L. Butler, R. Davidson, G. Zacharakis, B. Holloway, R. |
Citation: | Intensive Care Medicine, 2006; 32(9):1365-1370 |
Publisher: | Springer |
Issue Date: | 2006 |
ISSN: | 0342-4642 1432-1238 |
Abstract: | <h4>Objective</h4>Delayed gastric emptying (GE) is common both in critical illness and in patients with diabetes mellitus (DM). The effect of DM on the incidence of slow GE in these patients is unknown. We evaluated the effect of DM on liquid GE in critically ill patients.<h4>Methods</h4>Retrospective analysis of GE using a standard [13C]octanoic acid breath test in 12 type 2 DM patients compared with (a) 44 critically ill patients without DM, including (b) a subgroup of 15 age- and sex-matched patients and (c) 15 healthy volunteers. We determined the gastric emptying coefficient (GEC) and the gastric half-emptying time (t50). Mean APACHE II scores, blood glucose levels and use of morphine were similar between patient groups.<h4>Results</h4>GE was faster in critically ill patients with DM (t50 122 +/- 11 min, GEC: 3.8 +/- 0.3) than in patients without DM (t50 168 +/- 16 min, GEC 2.8 +/- 0.1) and in age- and sex-matched controls (t50 165 +/- 13 min, GEC 2.7 +/- 0.2) and was similar to that in healthy volunteers (t50 148 +/- 13 min, GEC 3.5 +/- 0.1). The proportion of patients with slow emptying (GEC < 3.2) was greater in non-DM (all = 56%, matched = 60%) than in DM patients (25%) and healthy subjects (26%).<h4>Conclusion</h4>Long-standing type diabetes mellitus is not a risk factor for slow GE in critically ill patients. |
Keywords: | Humans Diabetes Mellitus, Type 2 Critical Illness Breath Tests Respiration, Artificial APACHE Risk Factors Chi-Square Distribution Case-Control Studies Retrospective Studies Gastric Emptying Middle Aged Female Male |
DOI: | 10.1007/s00134-006-0228-0 |
Published version: | http://dx.doi.org/10.1007/s00134-006-0228-0 |
Appears in Collections: | Anaesthesia and Intensive Care publications Aurora harvest |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.