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Type: Journal article
Title: Analysis of datasets showing which compounds kill which organisms: inferring two systems
Author: Hutchinson, T.
Citation: European Journal of Medicinal Chemistry, 2004; 39(1):107-111
Publisher: Editions Scientifiques Medicales Elsevier
Issue Date: 2004
ISSN: 0223-5234
Statement of
T. P. Hutchinson
Abstract: Experiments are sometimes conducted to show which of several compounds is successful at inactivating which of several microorganisms. This paper proposes a method of analysing the datasets obtained. The example refers to 33 compounds (2,4-dihydroxythiobenzanilides) and seven microorganisms (dermatophytes) [data from Eur. J. Med. Chem. 35 (2000) 393]. The conclusion is that two systems or modes of action are needed to explain the data.
Keywords: 2,4-Dihydroxythiobenzanilides; antifungal activity; dermatophytes; data condensation
Description: Copyright © 2003 Elsevier SAS. All rights reserved.
RMID: 0020065328
DOI: 10.1016/j.ejmech.2003.11.006
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Appears in Collections:Centre for Automotive Safety Research publications

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