Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/39322
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Type: Journal article
Title: Left atrial linear ablation to modify the substrate of atrial fibrillation using a new nonfluoroscopic imaging system
Author: Takahashi, Y.
Rotter, M.
Sanders, P.
Jais, P.
Hocini, M.
Hsu, L.
Pasquie, J.
Sacher, F.
Garrigue, S.
Clementy, J.
Haissaguerre, M.
Citation: Pace-pacing and Clinical Electrophysiology, 2005; 28(S1):S90-S93
Publisher: Futura Publ Co
Issue Date: 2005
ISSN: 0147-8389
1540-8159
Statement of
Responsibility: 
Yoshihide Takahashi, Martin Rotter, Prashanthan Sanders, Pierre Jaïs, Mélèze Hocini, Li-Fern Hsu, Jean-Luc Pasquié, Frédéric Sacher, Stéphane Garrigue, Jacques Clémenty, Michel Haïssaguerre
Abstract: Linear left atrial ablation is performed in combination with pulmonary vein (PV) isolation to improve the clinical results of atrial fibrillation (AF) ablation. These procedures require long procedures and fluoroscopic exposure. The aim of the present study was to evaluate the performance of a new, nonfluoroscopic, real-time, three-dimensional navigation system for linear ablation at the left atrial roof and mitral isthmus. The study included 44 patients (54 +/- 10 years of age, 5 women) with drug-refractory AF, who underwent roof line or mitral isthmus linear ablation after 4-PV isolation. In 22 patients, ablation was performed with the navigation system (test group), and in the remainders linear ablation was performed with fluoroscopic guidance alone (control group). Conduction block was achieved in 20 patients (91%) in test group, and 21 patients (95%) in the control group (ns). Use of the navigation system was associated with a shorter fluoroscopic exposure for roof line (5.6 +/- 3.0 minutes vs 8.7 +/- 5.0 minutes, P < 0.05), and a trend for mitral isthmus ablation (7.8 +/- 7.8 minutes vs 12.1 +/- 5.9 minutes). It was also associated with a trend toward shorter procedure times for roof line (15.3 +/- 8.6 minutes vs 22.9 +/- 16.8 minutes) and mitral isthmus line (20.2 +/- 15.8 minutes vs 32.0 +/- 7.6 minutes) but no difference in duration of radiofrequency delivery. There was no procedural complication. The use of this new nonfluoroscopic imaging system was associated with a shorter fluoroscopic exposure as well as a trend toward shorter duration of linear ablation procedures for AF.
Keywords: atrial fibrillation; catheter ablation; linear atrial ablation; mitral isthmus ablation
Description: The definitive version is available at www.blackwell-synergy.com
RMID: 0020071845
DOI: 10.1111/j.1540-8159.2005.00036.x
Published version: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1540-8159.2005.00036.x
Appears in Collections:Medicine publications

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