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https://hdl.handle.net/2440/46028
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Type: | Journal article |
Title: | Air swallowing belching acid and non-acid reflux in patients with functional dyspepsia |
Author: | Conchillo, J. Selimah, M. Bredenoord, A. Samsom, M. Smout, A. |
Citation: | Alimentary Pharmacology and Therapeutics, 2007; 2007(8):965-971 |
Publisher: | Blackwell Publishing Ltd |
Issue Date: | 2007 |
ISSN: | 0269-2813 1365-2036 |
Statement of Responsibility: | J. M. Conchillo; M. Selimah; A. J. Bredenoord; M. Samsom; A. J. P. M. Smout |
Abstract: | Frequent belching is a common symptom in patients with functional dyspepsia with a reported incidence up to 80%. We hypothesized that patients with functional dyspepsia possibly have a higher frequency of belching than healthy subjects secondary to frequent air swallowing. Aim To assess air swallowing, belching, acid and non-acid reflux patterns of patients with functional dyspepsia. Methods Combined 24-h oesophageal impedance and pH monitoring was performed in 10 functional dyspepsia patients and 10 controls. Analysis of the impedance-pH signals included incidence of air swallows, belching, acid and non-acid reflux. Results The incidence of air swallows in functional dyspepsia patients were significantly higher compared with controls (153 ± 15 vs. 79 ± 10, P < 0.001), while the incidence of liquid-only swallows were not significantly increased. The proportions of gas-containing reflux episodes (belches) and non-acid reflux episodes in functional dyspepsia patients were significantly higher when compared with controls (66.4 vs. 44.4%, P = 0.04 and 70.1 vs. 45.9%, P = 0.009, respectively). Conclusion Patients with functional dyspepsia swallow air more frequently than controls and this is associated with an increased incidence of non-acid gaseous gastro-oesophageal reflux. |
DOI: | 10.1111/j.1365-2036.2007.03279.x |
Published version: | http://dx.doi.org/10.1111/j.1365-2036.2007.03279.x |
Appears in Collections: | Aurora harvest Medicine publications |
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