Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/46948
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Type: Journal article
Title: Severe mucositis: How can nutrition help?
Author: Keefe, D.
Rassias, G.
O'Neil, L.
Gibson, R.
Citation: Current Opinion in Clinical Nutrition and Metabolic Care, 2007; 10(5):627-631
Publisher: Lippincott Williams & Wilkins
Issue Date: 2007
ISSN: 1363-1950
1535-3885
Statement of
Responsibility: 
Dorothy M Keefe; Georgina Rassias; Lisa O'Neil; Rachel J Gibson
Abstract: Purpose of review: To review the recent evidence on the effect of nutrition on the incidence and severity of mucositis following anticancer treatment. Recent findings: There have been many recent publications on mucositis and on nutrition in cancer, but very few on nutrition and mucositis in cancer. It is difficult to establish a definite link between nutritional status, nutritional interventions and mucositis. Malnutrition is probably a risk factor for mucositis, however, and some of the interventions that improve nutrition in cancer patients and reduce the risk of cancer in the general population work via mechanisms that might positively affect the development and course of mucositis. Whilst it can be tempting to extrapolate these findings to suggest that nutritional support can reduce the incidence and severity of mucositis, this would be premature. Summary: There may well be a link between nutritional status, nutritional supplementation, anticancer treatment and mucositis, but it is not yet proven; and mechanism-based, prospective, randomized studies are required to answer the question. This is likely to be an area of increased study in the future.
Keywords: Humans; Antineoplastic Agents; Nutritional Support; Risk Factors; Nutritional Status; Mucositis
Description: Copyright © 2007, Lippincott Williams & Wilkins.
RMID: 0020074349
DOI: 10.1097/MCO.0b013e3282bf90d6
Published version: http://www.co-clinicalnutrition.com/pt/re/conutrition/abstract.00075197-200709000-00011.htm
Appears in Collections:Medicine publications

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