Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/47047
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dc.contributor.authorWunderlich, K.en
dc.contributor.authorAbbey, C.en
dc.contributor.authorClayton, D.en
dc.contributor.authorSong, Y.en
dc.contributor.authorSchein, J.en
dc.contributor.authorGeorges, M.en
dc.contributor.authorCoppieters, W.en
dc.contributor.authorAdelson, D.en
dc.contributor.authorTaylor, J.en
dc.contributor.authorDavis, S.en
dc.contributor.authorGill, C.en
dc.date.issued2006en
dc.identifier.citationAnimal Genetics, 2006; 37(6):592-594en
dc.identifier.issn0268-9146en
dc.identifier.issn1365-2052en
dc.identifier.urihttp://hdl.handle.net/2440/47047-
dc.descriptionThe definitive version is available at www.blackwell-synergy.comen
dc.description.abstractThe polled locus has been mapped by genetic linkage analysis to the proximal region of bovine chromosome 1. As an intermediate step in our efforts to identify the polled locus and the underlying causative mutation for the polled phenotype, we have constructed a BACbased physical map of the interval containing the polled locus. Clones containing genes and markers in the critical interval were isolated from the TAMBT (constructed from Angus and Longhorn genomic DNA) and CHORI-240 (constructed from horned Hereford genomic DNA) BAC libraries and ordered based on fingerprinting and the presence or absence of 80 STS markers. A single contig spanning 2.5 Mb was assembled. Comparison of the physical order of STSs to the corresponding region of human chromosome 21 revealed the same order of genes within the polled critical interval. This contig of overlapping BAC clones from horned and polled breeds is a useful resource for SNP discovery and characterization of positional candidate genes.en
dc.description.statementofresponsibilityK. R. Wunderlich, C. A. Abbey, D. R. Clayton, Y. Song, J. E. Schein, M. Georges, W. Coppieters, D. L. Adelson, J. F. Taylor, S. L. Davis and C. A. Gilen
dc.language.isoenen
dc.publisherBlackwell Publishing Ltden
dc.source.urihttp://www3.interscience.wiley.com/journal/118596294/abstracten
dc.subjectBAC contig; bovine chromosome 1en
dc.titleA 2.5-Mb contig constructed from Angus Longhorn and horned Hereford DNA spanning the polled interval on bovine chromosome 1en
dc.typeJournal articleen
dc.identifier.rmid0020081273en
dc.identifier.doi10.1111/j.1365-2052.2006.01538.xen
dc.identifier.pubid42930-
pubs.library.collectionMolecular and Biomedical Science publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidAdelson, D. [0000-0003-2404-5636]en
Appears in Collections:Molecular and Biomedical Science publications
Environment Institute publications

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