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dc.contributor.authorTrunkvalterova, Z.en
dc.contributor.authorJavorka, M.en
dc.contributor.authorTonhajzerova, I.en
dc.contributor.authorJavorkova, J.en
dc.contributor.authorLazarova, Z.en
dc.contributor.authorJavorka, K.en
dc.contributor.authorBaumert, M.en
dc.identifier.citationPhysiological Measurement, 2008; 29(7):817-828en
dc.description.abstractMultiscale entropy (MSE) analysis provides information about complexity on various time scales. The aim of this study was to test whether MSE is able to detect autonomic dysregulation in young patients with diabetes mellitus (DM). We analyzed heart rate (HR) oscillations, systolic (SBP) and diastolic blood pressure (DBP) signals in 14 patients with DM type 1 and 14 age- and sex-matched healthy controls. SampEn values (scales 1–10) and linear measures were computed. HR: among the linear measures of heart rate variability significant differences between groups were only found for RMSSD (p = 0.043). MSE was significantly reduced on scales 2 and 3 in DM (p = 0.023 and 0.010, respectively). SBP and DBP: no significant differences were detected with linear measures. In contrast, MSE analysis revealed significantly lower SampEn values in DM on scale 3 (p = 0.039 for SBP; p = 0.015 for DBP). No significant correlations were found between MSE and linear measures. In conclusion, MSE analysis of HR, SBP and DBP oscillations is able to detect subtle abnormalities in cardiovascular control in young patients with DM and is independent of standard linear measures.en
dc.description.statementofresponsibilityZ Trunkvalterova, M Javorka, I Tonhajzerova, J Javorkova, Z Lazarova, K Javorka and M Baumerten
dc.publisherIOP Publishing Ltden
dc.rightsCopyright © Institute of Physics and IOP Publishing Limited 2008.en
dc.subjectHumans; Diabetes Mellitus, Type 1; Blood Pressure; Heart Rate; Entropy; Adult; Female; Maleen
dc.titleReduced short-term complexity of heart rate and blood pressure dynamics in patients with diabetes mellitus type 1: multiscale entropy analysisen
dc.typeJournal articleen
pubs.library.collectionElectrical and Electronic Engineering publicationsen
dc.identifier.orcidBaumert, M. [0000-0003-2984-2167]en
Appears in Collections:Electrical and Electronic Engineering publications

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