Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/51000
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dc.contributor.authorCasson, R.en
dc.contributor.authorMarshall, D.en
dc.contributor.authorNewland, H.en
dc.contributor.authorMcGovern, S.en
dc.contributor.authorMuecke, J.en
dc.contributor.authorTan, E.en
dc.contributor.authorSelva-Nayagam, D.en
dc.contributor.authorAung, T.en
dc.date.issued2009en
dc.identifier.citationEye, 2009; 23(4):933-939en
dc.identifier.issn0950-222Xen
dc.identifier.issn1476-5454en
dc.identifier.urihttp://hdl.handle.net/2440/51000-
dc.description© 2009 The Royal College of Ophthalmologistsen
dc.description.abstractPURPOSE: To determine risk factors for early angle-closure disease (AD) in a Burmese population. METHODS: A cross-sectional, population-based survey of the inhabitants, 40 years of age and over, from villages in the Meiktila District was performed; 2481 eligible participants were identified, 2076 participated in the study, and 2050 could be categorized as having early AD (defined by the presence of so-called occludable angles (<90 degrees of posterior trabecular meshwork visible on gonioscopy), but without glaucomatous optic neuropathy). The ophthalmic examination included Snellen visual acuity, slit-lamp examination, tonometry, gonioscopy, biometry, and dilated stereoscopic fundus examination. RESULTS: The mean axial length (AL) and anterior chamber depth (ACD) in those with occludable angles were 21.9 and 2.60 mm, respectively; in those with non-occludable angles, the corresponding lengths were 22.74 and 2.84 mm, respectively (P<0.001 for both comparisons). In the univariate analyses, age, female gender, nuclear and cortical cataract, steeper corneal curvature, more anterior lens position, and myopia were also significantly associated with occludability. In the multivariate analysis, age, AL, ACD, and nuclear cataract were significantly associated with occludability. CONCLUSION: In this Burmese population, those with occludable angles had significantly shorter ALs, ACDs, and thicker lenses than those without occludable angles. In multivariate analysis, increasing age, decreasing AL, decreasing ACD, and nuclear cataract were significant predictors of early AD. The presence of nuclear cataract per se should raise clinical suspicion of the possibility of AD in this population.en
dc.description.statementofresponsibilityR. J. Casson, D. Marshall, H. S. Newland, S. McGovern, J. Muecke, E. W. H. Tan, D Selva and T. Aungen
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.subjectangle-closure glaucoma; ocular biometry; nuclear cataracten
dc.titleRisk factors for early angle-closure disease in a Burmese population: the Meiktila Eye Studyen
dc.typeJournal articleen
dc.identifier.rmid0020090540en
dc.identifier.doi10.1038/eye.2008.102en
dc.identifier.pubid39006-
pubs.library.collectionOpthalmology & Visual Sciences publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidCasson, R. [0000-0003-2822-4076]en
dc.identifier.orcidSelva-Nayagam, D. [0000-0002-2169-5417]en
Appears in Collections:Opthalmology & Visual Sciences publications

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