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Type: Journal article
Title: Hot summers and heart failure: Seasonal variations in morbidity and mortality in Australian heart failure patients (1994-2005)
Author: Inglis, S.
Clark, R.
Shakib, S.
Wong, T.
Molaee, P.
Wilkinson, D.
Stewart, S.
Citation: European Journal of Heart Failure, 2008; 10(6):540-549
Publisher: Elsevier Science BV
Issue Date: 2008
ISSN: 1388-9842
Statement of
Sally C. Inglis, Robyn A. Clark, Sepehr Shakib, Denis T. Wong, Payman Molaee, David Wilkinson and Simon Stewart
Abstract: Background: There are minimal reports of seasonal variations in chronic heart failure (CHF)-related morbidity and mortality beyond the northern hemisphere. Aims and methods: We examined potential seasonal variations with respect to morbidity and all-cause mortality over more than a decade in a cohort of 2961 patients with CHF from a tertiary referral hospital in South Australia subject to mild winters and hot summers. Results: Seasonal variation across all event-types was observed. CHF-related morbidity peaked in winter (July) and was lowest in summer (February): 70 (95% CI: 65 to 76) vs. 33 (95% CI: 30 to 37) admissions/1000 at risk (p<0.005). All-cause admissions (113 (95% CI: 107 to 120) vs. 73 (95% CI 68 to 79) admissions/1000 at risk, p<0.001) and concurrent respiratory disease (21% vs. 12%,p<0.001) were consistently higher in winter. 2010 patients died, mortality was highest in August relative to February: 23 (95% CI: 20 to 27) vs. 12 (95% CI: 10 to 15) deaths per 1000 at risk, p<0.001. Those aged 75 years or older were most at risk of seasonal variations in morbidity and mortality. Conclusion: Seasonal variations in CHF-related morbidity and mortality occur in the hot climate of South Australia, suggesting that relative (rather than absolute) changes in temperature drive this global phenomenon.
Keywords: Chronic heart failure; Mortality; Morbidity; Seasonality; Temperature; Hospitalisation
Description: © 2008 European Society of Cardiology
RMID: 0020081378
DOI: 10.1016/j.ejheart.2008.03.008
Appears in Collections:Pharmacology publications

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