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https://hdl.handle.net/2440/56495
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Type: | Journal article |
Title: | Protein nanofibres of defined morphology prepared from mixtures of crude crystallins |
Author: | Garvey, M. Gras, S. Meehan, S. Meade, S. Carver, J. Gerrard, J. |
Citation: | International Journal of Nanotechnology, 2009; 6(3-4):258-273 |
Publisher: | Inderscience Publishers |
Issue Date: | 2009 |
ISSN: | 1475-7435 1741-8151 |
Statement of Responsibility: | M. Garvey, S.L. Gras, S. Meehan, S.J. Meade, J.A. Carver, J.A. Gerrard |
Abstract: | Self assembling protein nanofibres have great potential within the nanotechnology industry. To realise this potential, nanofibres need to be manufactured on a commercial scale. To date, amyloid fibrils, a form of protein nanofibre with desirable bionanotechnological properties, have only been produced using expensive and time-costly, small-scale methods. This paper describes the production of protein nanofibres from semi-pure and crude mixtures of bovine crystallin proteins, currently a waste product in the meat industry. These nanofibres displayed amyloid fibril characteristics. Moreover, distinct fibre morphologies were observed dependent upon the formation conditions adopted. This research shows that amyloid fibrils can be inexpensively produced from crude crystallin protein mixtures, making them a potential industrial source for protein nanofibres. |
Keywords: | amyloid fibrils protein nanofibres bovine crystallins WAXS TEM self assembly nanotechnology fibre morphologies. |
DOI: | 10.1504/IJNT.2009.022918 |
Published version: | http://dx.doi.org/10.1504/ijnt.2009.022918 |
Appears in Collections: | Aurora harvest Physics publications |
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