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https://hdl.handle.net/2440/57946
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Type: | Journal article |
Title: | Reasons for improved survival from ovarian cancer in New South Wales, Australia, between 1980 and 2003: Implications for cancer control |
Author: | Tracey, E. Roder, D. Francis, J. Zorbas, H. Hacker, N. Bishop, J. |
Citation: | International Journal of Gynecological Cancer, 2009; 19(4):591-599 |
Publisher: | Blackwell Science Inc |
Issue Date: | 2009 |
ISSN: | 1048-891X 1525-1438 |
Statement of Responsibility: | Tracey, Elizabeth; Roder, David; Francis, Jane; Zorbas, Helen M; Hacker, Neville F; and Bishop, James F. |
Abstract: | We analyzed New South Wales Central Cancer Registry data for 1980-2003, to determine time trends in case fatality from ovarian cancer, after adjusting for stage, histological, and sociodemographic factors, and to consider service-delivery and research implications. After adjusting for covariates, the relative risk (95% confidence limit) of ovarian-cancer death reduced to 0.51 (0.46, 0.57) for 1999-2003 compared with 1980-1983. Relative risks were higher for adenocarcinomas and other specified and unspecified cancers than serous carcinomas, but lower for endometrioid carcinomas, sex cord-stromal and germ cell tumors. The probability of diagnosis with localized as opposed to more advanced disease was lower in older patients, the lowest socioeconomic stratum, women born in non-English-speaking countries, and more recent diagnostic periods. Approximately 61% of ovarian cancers had distant metastases at diagnosis in 1999-2003. Poorer survivals apply to older patients. Research directed at finding an effective screening test for epithelial ovarian cancer remains a priority. |
Keywords: | Humans Ovarian Neoplasms Mass Screening Neoplasm Staging Registries Logistic Models Proportional Hazards Models Age Factors Socioeconomic Factors Adult Aged Aged, 80 and over Middle Aged New South Wales Female |
Rights: | Copyright © 2009 by IGCS and ESGO |
DOI: | 10.1111/IGC.0b013e3181a3a436 |
Published version: | http://dx.doi.org/10.1111/igc.0b013e3181a3a436 |
Appears in Collections: | Aurora harvest Public Health publications |
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