Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/58474
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dc.contributor.authorBell, R.en
dc.contributor.authorHealy, D.en
dc.contributor.authorRobertson, D.en
dc.contributor.authorJobling, T.en
dc.contributor.authorOehler, M.en
dc.contributor.authorEdwards, A.en
dc.contributor.authorShekleton, P.en
dc.contributor.authorOldham, J.en
dc.contributor.authorPiessens, S.en
dc.contributor.authorTeoh, M.en
dc.contributor.authorMamers, P.en
dc.contributor.authorTaylor, N.en
dc.contributor.authorWalker, F.en
dc.date.issued2009en
dc.identifier.citationMenopause-The Journal of the North American Menopause Society, 2009; 16(6):1-7en
dc.identifier.issn1072-3714en
dc.identifier.issn1530-0374en
dc.identifier.urihttp://hdl.handle.net/2440/58474-
dc.description.abstractOBJECTIVE: We have previously reported on the point prevalence of ovarian lesions detected by transvaginal ultrasound (TVU) in 515 asymptomatic women at least 5 years postmenopause. The aims of this study were to report, in the same women, on the repeatability of visualization of the ovaries (TVU) and the natural history of ovarian lesions seen at baseline but not treated surgically and to assess whether any women developed new ovarian abnormalities 12 months later. METHODS: The study involved a cohort of 515 postmenopausal women recruited from the community, at least 5 years past their last period. They were assessed at baseline and again after 12 months with TVU and serum levels of inhibin and CA-125. RESULTS: The right and left ovaries were seen on both occasions in 80% and 68% of women, respectively. Of the 49 women who had an ovarian lesion at baseline, did not undergo surgery at that time, and had a follow-up TVU, the lesion was unchanged 12 months later in 30 women. Four women developed a new ovarian lesion within the 12 months. None of the 14 women who underwent surgery on the basis of the ovarian appearance at baseline, or the 2 who had surgery on the basis of the ovarian appearance at follow-up, had an ovarian malignancy. CONCLUSIONS: The use of TVU in women at least 5 years after menopause is problematic because the ovaries cannot be visualized in all women and because TVU has the potential to identify many benign lesions that would otherwise remain undetected. These are important considerations in weighing up the risks and benefits of using TVU as a screening tool.en
dc.description.statementofresponsibilityRobin J. Bell, David L. Healy, David M. Robertson, Tom Jobling, Martin K. Oehler, Andrew Edwards, Paul Shekleton, Jacqueline Oldham, Sofie Piessens, Mark Teoh, Pamela Mamers, Nancy Taylor, Frances Walkeren
dc.description.urihttp://www.ncbi.nlm.nih.gov/pubmed/19574938en
dc.language.isoenen
dc.publisherLippincott Williams & Wilkinsen
dc.rights©2009 The North American Menopause Societyen
dc.subjectOvarian health; Transvaginal ultrasound; Inhibin; CA-125en
dc.titleOvarian status in healthy postmenopausal women: follow-up 12 months after transvaginal ultrasounden
dc.typeJournal articleen
dc.identifier.rmid0020095563en
dc.identifier.doi10.1097/gme.0b013e3181aa1c93en
dc.identifier.pubid35662-
pubs.library.collectionObstetrics and Gynaecology publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
Appears in Collections:Obstetrics and Gynaecology publications

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