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|Title:||Axonal and neuronal amyloid precursor protein immunoreactivity in the brains of guinea pigs given tunicamycin|
|Citation:||Veterinary Pathology, 2000; 37(6):677-680|
|Publisher:||Amer Coll Vet Pathologist|
|Abstract:||Amyloid precursor protein (APP) immunocytochemistry was used to study axonal and neuronal changes in guinea pig brains exposed to tunicamycin. Substantial axonal injury was found in ischemic-hypoxic foci and more generally, but this injury was not readily appreciable in conventionally stained sections. Neuronal perikaryal APP expression was also widely distributed, possibly as an acute phase response to this neurotoxin.|
|Keywords:||Brain; Neurons; Axons; Animals; Guinea Pigs; Amyloid beta-Protein Precursor; Tunicamycin; Anti-Bacterial Agents; Immunohistochemistry; Brain Chemistry|
|Appears in Collections:||Pathology publications|
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