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https://hdl.handle.net/2440/59764
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DC Field | Value | Language |
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dc.contributor.author | van Wijk, M. | - |
dc.contributor.author | Benninga, M. | - |
dc.contributor.author | Davidson, G. | - |
dc.contributor.author | Haslam, R. | - |
dc.contributor.author | Omari, T. | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Journal of Pediatrics, 2010; 156(5):744-759 | - |
dc.identifier.issn | 0022-3476 | - |
dc.identifier.issn | 1097-6833 | - |
dc.identifier.uri | http://hdl.handle.net/2440/59764 | - |
dc.description.abstract | <h4>Objective</h4>To investigate the threshold amount of constantly infused feed needed to trigger lower esophageal sphincter relaxation (TLESR) in the right lateral position (RLP) and left lateral position (LLP).<h4>Study design</h4>Eight healthy infants (3 male; gestational age: 32.9 +/- 2.4 weeks; corrected age: 36.1 +/- 1.3 weeks) were studied using an esophageal impedance-manometry catheter incorporating an intragastric infusion port. After tube placement, infants were randomly positioned in RLP or LLP. They were then tube-fed their normal feed (62.5 [40 to 75] mL) at an infusion rate of 160 mL/h. Recordings were made during the feed and 15 minutes thereafter. The study was repeated with the infant in the opposite position.<h4>Results</h4>More TLESRs were triggered in the RLP compared with LLP (4.0 [3.0 to 6.0] vs 2.5 [1.0 to 3.0], P = .027). First TLESR occurred at a significantly lower infused volume in RLP compared with LLP (10.6 +/- 9.4 vs 21.0 +/- 4.9 mL, P = .006). The percentage of feed infused at time of first TLESR was significantly lower in RLP compared with LLP (17.6% +/- 15.5% vs 35.4% +/- 8.02%, P = .005).<h4>Conclusions</h4>In the RLP, TLESRs and gastroesophageal reflux are triggered at volumes unlikely to induce gastric distension. | - |
dc.description.statementofresponsibility | Michiel P. van Wijk, Marc A. Benninga, Geoffrey P. Davidson, Ross Haslam, and Taher I. Omari | - |
dc.language.iso | en | - |
dc.publisher | Mosby Inc | - |
dc.rights | Copyright © 2010 Mosby, Inc. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.jpeds.2009.11.006 | - |
dc.subject | Esophageal Sphincter, Lower | - |
dc.subject | Humans | - |
dc.subject | Gastroesophageal Reflux | - |
dc.subject | Infant, Premature, Diseases | - |
dc.subject | Enteral Nutrition | - |
dc.subject | Manometry | - |
dc.subject | Electric Impedance | - |
dc.subject | Posture | - |
dc.subject | Muscle Relaxation | - |
dc.subject | Infant, Newborn | - |
dc.subject | Infant, Premature | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.title | Small volumes of feed can trigger transient lower esophageal sphincter relaxation and gastroesophageal reflux in the right lateral position in infants | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.jpeds.2009.11.006 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Omari, T. [0000-0001-5108-7378] | - |
Appears in Collections: | Aurora harvest Paediatrics publications |
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