Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/66221
Type: Journal article
Title: Computer-assisted osteodensitometry following total hip arthroplasty
Author: Reilly, Keryn
Munro, Jacob Terrill
Pitto, Rocco P.
Citation: Expert Review of Medical Devices, 2006; 3(6):763-768
Publisher: Expert Reviews
Issue Date: 2006
ISSN: 1743-4440
School/Discipline: Orthopaedics and Trauma
Statement of
Responsibility: 
Keryn Reilly, Jacob Munro and Rocco P. Pitto
Abstract: Several factors, including polyethylene wear debris, implant micromotion and stress shielding, can cause bone loss and fixation failure following total hip arthroplasty. Various techniques have been utilized in an effort to detect bone density loss in vivo with varying success. Quantitative computed tomography (qCT)-assisted osteodensitometry has been shown to be useful in assessing the in vivo structural bone changes after total hip arthroplasty. It has high resolution, accuracy and reproducibility, making it a useful tool for research purposes. qCT osteodensitometry is able to differentiate between cortical and cancellous bone structures, and to assess the bone/implant interface. It provides valuable information about the pattern of stress shielding that occurs around the prosthesis. qCT-assisted osteodensitometry can show early bony changes, which may provide information about the quality of implant fixation and surrounding bone adaptation. In conjunction with finite-elements analysis, qCT is able to generate accurate patient-specific meshes on which to model implants and their effect on bone remodeling. This technology can be useful in order to predict bone remodeling and quality of implant fixation using prostheses with different design and/or biomaterials. In future, this tool could be used for preclinical validation of new implants before their introduction in the marketplace.
Keywords: Bone mineral density; osteodensitometry; quantitative computed tomography; total hip arthroplasty
Rights: COPYRIGHT 2006 Expert Reviews Ltd.
RMID: 0020111624
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Appears in Collections:Orthopaedics and Trauma publications

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