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Type: Journal article
Title: Evidence for anti-osteoporosis therapy in acute fracture situations - recommendations of a multidisciplinary workshop of the international society for fracture repair
Author: Goldhahn, J.
Little, D.
Mitchell, P.
Fazzalari, N.
Reid, I.
Aspenberg, P.
Marsh, D.
Citation: Bone, 2010; 46(2):267-271
Publisher: Elsevier Science Inc
Issue Date: 2010
ISSN: 8756-3282
Statement of
Jörg Goldhahn, David Little, Paul Mitchell, Nicola Fazzalari, Ian R. Reid, Per Aspenberg, David Marsh on behalf of the ISFR working group drugs and fracture repair
Abstract: The International Society for Fracture Repair convened a multidisciplinary workshop to assess the current evidence around the interaction between anti-osteoporosis drugs and the healing of incident fractures, with a view to making recommendations for clinical practice. The consensus was that there is no evidence-based reason to withhold anti-resorptive therapy while a fracture heals, whether or not the patient was taking such therapy when the fracture occurred. The workshop also considered existing models of service provision for secondary prevention and concluded that the essential ingredient for reliable delivery is the inclusion of a dedicated coordinator role. Several unresolved issues were defined as subjects for further research, including the question of whether continuous long-term administration of anti-resorptives may impair bone quality. The rapidly changing area requires re-assessment of drugs and their interaction with fracture healing in the near future.
Keywords: Fracture healing; Osteoporosis; Drugs; Drug interaction
Rights: Copyright © 2009 Elsevier Inc. All rights reserved.
RMID: 0020100142
DOI: 10.1016/j.bone.2009.10.004
Appears in Collections:Medical Sciences publications

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