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https://hdl.handle.net/2440/67376
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Type: | Journal article |
Title: | Simplified COPD screening: Validation of the PiKo-6® in primary care |
Other Titles: | Simplified COPD screening: Validation of the PiKo-6(R) in primary care |
Author: | Frith, P. Crockett, A. Beilby, J. Marshall, D. Attewell, R. Ratnanesan, A. Gavagna, G. |
Citation: | Primary Care Respiratory Journal, 2011; 20(2):190-198 |
Publisher: | Strategic Medical Publishing |
Issue Date: | 2011 |
ISSN: | 1471-4418 1475-1534 |
Statement of Responsibility: | Peter Frith, Alan Crockett, Justin Beilby, David Marshall, Robyn Attewell, Avnesh Ratnanesan, Guy Gavagna |
Abstract: | <h4>Aims</h4>To determine the accuracy of the forced expiratory volume ratio at one and six seconds (FEV1/FEV6) using a hand-held, expiratory flow meter (PiKo-6®, nSpire Health, Inc.) to screen for chronic obstructive pulmonary disease (COPD) in primary care settings.<h4>Methods</h4>Current and former smokers (≥ 50 years old) with no previous respiratory diagnosis (case finding [CF] = 204 subjects) or with an asthma diagnosis (differential diagnosis [DD] = 93 subjects) were evaluated using validated questionnaires, pre-bronchodilator (BD) FEV1/FEV6 and post-BD FEV1/forced vital capacity (FVC) spirometry.<h4>Results</h4>The PiKo-6® FEV1/FEV6 showed good sensitivity and specificity (areas under the Receiver Operating Characteristic curves [95% confidence intervals]: CF = 0.85 [0.79, 0.90]; DD = 0.88 [0.80, 0.96]) and exceeded the accuracy of the questionnaires. An FEV1/FEV6 cutoff < 0.75 provided optimal sensitivity (CF = 81%; DD = 86%) and specificity (CF = 71%; DD = 67%) for COPD screening.<h4>Conclusions</h4>The PiKo-6® allows simple and reliable screening for COPD which could optimise early referral for spirometry and early, targeted interventions for COPD. |
Keywords: | COPD primary care spirometry diagnostic questionnaire early diagnosis PiKo-6® mini-spirometer |
Rights: | © 2011 Primary Care Respiratory Society UK. All rights reserved. |
DOI: | 10.4104/pcrj.2011.00040 |
Published version: | http://dx.doi.org/10.4104/pcrj.2011.00040 |
Appears in Collections: | Aurora harvest 5 Medical Sciences publications |
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