Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||The molecular basis of fragile sites in human chromosomes|
|Citation:||Current Opinion in Genetics and Development, 1995; 5(3):323-327|
|Publisher:||Current Biology Ltd.|
|Grant R. Sutherland and Robert I. Richards|
|Abstract:||Fragile sites on chromosomes have been classified into a number of groups according to their frequency and the conditions required to induce them. A number of the rare folate-sensitive fragile sites have been characterized and shown to be amplified methylated CCG trinucleotide repeats. One common fragile site has been partly characterized and appears to be a region of fragility, rather than a single site.|
|Keywords:||Chromosomes, Human; Humans; Chromosome Fragility; Aphidicolin; Culture Techniques; Sequence Analysis, DNA; Gene Expression Regulation; Repetitive Sequences, Nucleic Acid; Mutation; Genes; Chromosome Fragile Sites|
|Appears in Collections:||Paediatrics publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.