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|Title:||Molecular Characterization of a Nonneuronal Human Unc18 Homolog|
|Citation:||Genomics, 1996; 37(1):19-23|
|Abstract:||A cDNA clone encoding a human homolog of the Caenorhabditis elegans unc-18 gene was identified following random sequencing of clones from IL-2-activated human NK cells. This cDNA clone is related to the nonneuronal Munc-18b and so has been called Hunc-18b. The Hunc-18b transcripts were found in most human tissues, with the exception of brain and skeletal muscle, and in cells from all lymphoid lineages. The Hunc-18b gene was localized to human chromosome 19p13.2-p13.3, and the mouse homolog, Munc-18b, was mapped to the proximal region of mouse Chromosome 8.|
|Keywords:||Chromosomes, Human, Pair 19; Animals; Humans; Mice; Vesicular Transport Proteins; Nerve Tissue Proteins; DNA, Complementary; In Situ Hybridization, Fluorescence; Chromosome Mapping; Cloning, Molecular; Amino Acid Sequence; Sequence Homology, Amino Acid; Molecular Sequence Data; Munc18 Proteins|
|Appears in Collections:||Paediatrics publications|
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