Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/74652
Type: Patent
Title: Comparative Genomic Hybridization
Author: Hussey, Nicole Dominique
Hu, Dong Gui
Issue Date: 2006
Assignee: Adelaide Research & Innovation Pty Ltd
School/Discipline: School of Paediatrics and Reproductive Health : Obstetrics and Gynaecology
Contributor: Fan Zheng
Statement of
Responsibility: 
Invented by N.D. Hussey, D.G. Hu; Assigned to Adelaide Research and Innovation Pty Ltd; Fan Zheng agent for the inventors.
Abstract: The present invention relates to a method of comparing at least one chromosome or part thereof from a cell with a first karyotype with the corresponding chromosome or part thereof from a cell with a second karyotype. The method includes the steps of: (a) amplifying DNA from an isolated chromosome or part of an isolated chromosome; (b) attaching the amplified DNA to a solid substrate; (c) amplifying DNA from one or more cells with a first karyotype and amplifying DNA from one or more cells with a second karyotype; (d) labelling the amplified DNA from the one or more cells with a first karyotype with a first label, and labelling the amplified DNA from the one or more cells with a second karyotype with a second label, wherein the first and second labels are detectably different; (e) hybridizing the amplified and labelled DNA from the one or more cells with a first karyotype to the amplified DNA attached to the solid substrate, and hybridizing the amplified and labelled DNA from the one or more cells with a second karyotype to the amplified DNA attached to the solid substrate; and (f) comparing the relative amount of first and second labels hybridized to the amplified DNA attached to the solid substrate.
Keywords: CN 200480015169
Description: PATENT: N.D. Hussey, D.G. Hu (Assigned to Adelaide Research and Innovation Pty Ltd). CN 200480015169 (PCT/AU04/00429) filed Apr. 2, 2004; published Jul. 5, 2006
RMID: 0020114470
Description (link): http://59.151.93.237/sipo_EN/search/detail.do?method=view&parm=16b414c21a2f19d11b2c18401bcd1a5f183219461acb1be11a781c4407f92f231f5221f222572195236c20482755275723ca24be2221222525702494250d26c0274025822c3f29092a7c29a02d6d2d6f28fa2ed62bd12c892f482c34330947932f5c2c0a2ac731b9333c316c366534e7318235ee337934f1360837f03747371b371a34e231bf38f13b04390c3e0d3f6f39ea3dc63c573d6d3e683e4c26d918c33ffe3c523c273e354334405c47c545774302408e442d45bd47e046bc462f46af46ea4492416f4721
Appears in Collections:Obstetrics and Gynaecology publications

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