Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/74685
Type: Patent
Title: Comparative Genomic Hybridization
Author: Hussey, Nicole Dominique
Hu, Dong Gui
Issue Date: 2009
Assignee: Adelaide Research & Innovation Pty Ltd
School/Discipline: School of Paediatrics and Reproductive Health : Obstetrics and Gynaecology
Contributor: Phillips Ormonde Fitzpatrick
Statement of
Responsibility: 
Invented by N. D. Hussey, D. G. Hu; Assigned to Adelaide Research & Innovation Pty Ltd; Phillips Ormonde Fitzpatrick agents for inventors.
Abstract: The present invention relates to a method of comparing at least one chromosome or part thereof from a cell with a first karyotype with the corresponding chromosome or part thereof from a cell with a second karyotype. The method includes the steps of: (a) amplifying DNA from an isolated chromosome or part of an isolated chromosome; (b) attaching the amplified DNA to a solid substrate; (c) amplifying DNA from one or more cells with a first karyotype and amplifying DNA from one or more cells with a second karyotype; (d) labelling the amplified DNA from the one or more cells with a first karyotype with a first label, and labelling the amplified DNA from the one or more cells with a second karyotype with a second label, wherein the first and second labels are detectably different; (e) hybridizing the amplified and labelled DNA from the one or more cells with a first karyotype to the amplified DNA attached to the solid substrate, and hybridizing the amplified and labelled DNA from the one or more cells with a second karyotype to the amplified DNA attached to the solid substrate; and (f) comparing the relative amount of first and second labels hybridized to the amplified DNA attached to the solid substrate.
Keywords: AU 2004/225908 B2
Description: PATENT: N. D. Hussey, D. G. Hu (Assignee: Adelaide Research & Innovation Pty Ltd). AU 2004/225908 B2 (WO 2004/088310 A1) filed Apr 2, 2004; published (WIPO) Oct 14, 2004; accepted journal date May 28, 2009.
RMID: 0020114494
Description (link): http://www.patentlens.net/patentlens/patent/AU_2004_225908_B2/en/
Appears in Collections:Obstetrics and Gynaecology publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.